RBM23 and BHLHE40

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RBM23	BHLHE40
Description		RNA binding motif protein 23	basic helix-loop-helix family member e40
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Membrane Ribonucleoprotein Complex	Nuclear Chromatin Nucleus Cytoplasm Nuclear Body
	Molecular Function	RNA Binding Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Protein Homodimerization Activity BHLH Transcription Factor Binding MRF Binding Protein Heterodimerization Activity E-box Binding
	Biological Process	MRNA Processing Regulation Of RNA Metabolic Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Circadian Rhythm Anterior/posterior Pattern Specification Cell Differentiation Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Regulation Of Neurogenesis
Pathways			BMAL1:CLOCK,NPAS2 activates circadian gene expression
Drugs
Diseases
GWAS		Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical amyloid beta load ( 29860282) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 31604244) Psoriasis vulgaris ( 26626624) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355)
Interacting Genes		25 interacting genes: BHLHE40 CDK6 CEP126 CHERP ESR1 FAM9B FBXO7 GTF3C1 MAGEA11 MAGED1 MED31 PGR POLA2 PRMT5 PTN QKI RBFOX2 RBM25 RBM39 RBM4 RPA1 SRPK1 SRPK2 TRIM27 TUBA4A	51 interacting genes: AAMP AANAT APH1A ARNTL BHLHE41 BRD7 CALML3 CCNK CDPF1 CHD3 COX5B DAB1 EHHADH ENO1 FBLN1 GMCL2 HDAC1 HIVEP1 HNRNPLL KRTAP23-1 LARP4 MAGED1 MYOD1 NAA50 NOC4L NUMBL PDE6G PLEKHB2 PRKAA1 RBFOX1 RBM23 RBPMS RHOBTB3 RHOJ SETDB1 SIN3A SMARCB1 SMYD1 SOX15 STAT3 STK19 TCF3 TLE5 TOB2 TOLLIP TTC23 TXNL4B UBE2I VAC14 VIM ZHX1
Entrez ID		55147	8553
HPRD ID		15227	16050
Ensembl ID		ENSG00000100461	ENSG00000134107
Uniprot IDs		A0A0S2Z5D9 A0A0S2Z5I1 A0A0S2Z5J3 B7Z8M4 G3XAP0 Q86U06	O14503 Q6IB83
PDB IDs		2CQ4 2DNZ
Enriched GO Terms of Interacting Partners?
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