Description |
egl-9 family hypoxia inducible factor 1 |
heat shock protein 90 alpha family class B member 1 |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Geldanamycin
- 9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine
- Radicicol
- Tanespimycin
- SNX-5422
- 4-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOL
- 8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE
- 4-{4-[4-(3-AMINOPROPOXY)PHENYL]-1H-PYRAZOL-5-YL}-6-CHLOROBENZENE-1,3-DIOL
- (5E)-14-CHLORO-15,17-DIHYDROXY-4,7,8,9,10,11-HEXAHYDRO-2-BENZOXACYCLOPENTADECINE-1,12(3H,13H)-DIONE
- (5Z)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE
- (5E)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE
- (5Z)-13-CHLORO-14,16-DIHYDROXY-3,4,7,8,9,10-HEXAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,11(12H)-DIONE
- METHYL 3-CHLORO-2-{3-[(2,5-DIHYDROXY-4-METHOXYPHENYL)AMINO]-3-OXOPROPYL}-4,6-DIHYDROXYBENZOATE
- 2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL 5-CHLORO-2,4-DIHYDROXYBENZOATE
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Diseases |
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GWAS |
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- Waist-to-hip ratio adjusted for BMI ( 26426971)
- Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
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Interacting Genes |
13 interacting genes:
EPAS1
FKBP8
HIF1A
HIF3A
HSP90AA1
HSP90AB1
ING4
KRAS
OS9
PLD1
SRC
VHL
ZNF281
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55 interacting genes:
ACD
AKT1
ARHGAP1
CCT2
CDC37L1
CDKN2A
CHORDC1
CHUK
CLIC4
CSNK2A1
CYP17A1
DDX24
EGFR
EGLN1
ESR1
ESRRB
FCHSD2
HSF1
HSPB1
IKBKB
IKBKE
IKBKG
KEAP1
MAP3K14
MAP3K3
MAPK6
MKNK1
NR2C2
NR3C1
NR4A1
POT1
PPID
PTEN
PTGES3
RHOBTB2
SERPINB5
SGTA
SIRPA
SLC34A1
STARD13
STAT1
STAT3
SUMO2
TAF1D
TBK1
TERF1
TINF2
TNNT1
TP53
TSSK6
UBE3A
UNC45A
USP50
WASL
YWHAB
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Entrez ID |
54583 |
3326 |
HPRD ID |
06971 |
06763 |
Ensembl ID |
ENSG00000135766
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ENSG00000096384
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Uniprot IDs |
Q9GZT9
R4SCQ0
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A0A024RD80
B4DGL0
P08238
Q6PK50
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PDB IDs |
2G19
2G1M
2HBT
2HBU
2Y33
2Y34
3HQR
3HQU
3OUH
3OUI
3OUJ
4BQW
4BQX
4BQY
4JZR
4KBZ
4UWD
5A3U
5L9B
5L9R
5L9V
5LA9
5LAS
5LAT
5LB6
5LBB
5LBC
5LBE
5LBF
5OX5
5OX6
5V18
6NMQ
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1QZ2
1UYM
2L6J
3FWV
3NMQ
3PRY
3UQ3
5FWK
5FWL
5FWM
5FWP
5UC4
5UCH
5UCI
5UCJ
6N8W
6N8Y
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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