DEF6 and CDC42EP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		DEF6	CDC42EP1
Description		DEF6 guanine nucleotide exchange factor	CDC42 effector protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Filopodium Perinuclear Region Of Cytoplasm	Cytoplasm Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Endomembrane System
	Molecular Function	Protein Binding	Protein Binding GTP-Rho Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process		Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		Height ( 18391951) Systemic lupus erythematosus ( 28714469)
Interacting Genes		15 interacting genes: APP BEGAIN CDC42 CDC42EP1 EIF4ENIF1 HOMEZ LCK PBXIP1 PLSCR1 PTK2 RAC1 RAC2 RHOA TCF4 ZAP70	10 interacting genes: CDC42 DEF6 FHL3 KRTAP4-12 MAPKAP1 MDFI PLSCR1 RBPMS RHOJ RHOQ
Entrez ID		50619	11135
HPRD ID		10869	07303
Ensembl ID		ENSG00000023892	ENSG00000128283
Uniprot IDs		Q9H4E7	Q00587
PDB IDs
Enriched GO Terms of Interacting Partners?
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