CDC42EP1 and MAPKAP1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CDC42EP1	MAPKAP1
Description		CDC42 effector protein 1	MAPK associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Endomembrane System	Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Cytoplasmic Vesicle TORC2 Complex
	Molecular Function	Protein Binding GTP-Rho Binding Cadherin Binding Involved In Cell-cell Adhesion	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Ras GTPase Binding Protein Kinase Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidic Acid Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Cell-cell Adhesion	Substantia Nigra Development Establishment Or Maintenance Of Actin Cytoskeleton Polarity Activation Of Protein Kinase B Activity Positive Regulation Of Peptidyl-serine Phosphorylation TORC2 Signaling Negative Regulation Of Ras Protein Signal Transduction Regulation Of Cellular Response To Oxidative Stress
Pathways			PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation
Drugs
Diseases
GWAS			Body mass index ( 28892062) Diverticular disease ( 30177863) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Medication use (calcium channel blockers) ( 31015401) Resting heart rate ( 27798624) Sleep duration ( 30531941) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		10 interacting genes: CDC42 DEF6 FHL3 KRTAP4-12 MAPKAP1 MDFI PLSCR1 RBPMS RHOJ RHOQ	9 interacting genes: ABCB1 AKT1 CDC42EP1 ECI1 MAPK8 NRAS PRKCA SGK1 YWHAG
Entrez ID		11135	79109
HPRD ID		07303	17464
Ensembl ID		ENSG00000128283	ENSG00000119487
Uniprot IDs		Q00587	A0A024R863 Q9BPZ7
PDB IDs			3VOQ 5ZCS
Enriched GO Terms of Interacting Partners?
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