CDC42EP1 and RHOQ

Number of citations of the paper that reports this interaction (PubMedID 10490598)
41

Data Source:
HPRD (two hybrid, in vitro)

		CDC42EP1	RHOQ
Description		CDC42 effector protein 1	ras homolog family member Q
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Endomembrane System	Cytoplasm Cytosol Cytoskeleton Actin Filament Plasma Membrane Cell Cortex Golgi-associated Vesicle Membrane Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Exosome
	Molecular Function	Protein Binding GTP-Rho Binding Cadherin Binding Involved In Cell-cell Adhesion	GTPase Activity Profilin Binding GTP Binding Protein Kinase Binding GBD Domain Binding
	Biological Process	Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Cell-cell Adhesion	Endocytosis Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Cell Shape Cell Migration Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Transcription By RNA Polymerase II GTP Metabolic Process Positive Regulation Of Glucose Import Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Filopodium Assembly Negative Regulation Of Protein Localization To Plasma Membrane
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Rho GTPase cycle RHO GTPases regulate CFTR trafficking
Drugs
Diseases
GWAS
Interacting Genes		10 interacting genes: CDC42 DEF6 FHL3 KRTAP4-12 MAPKAP1 MDFI PLSCR1 RBPMS RHOJ RHOQ	18 interacting genes: CDC42BPG CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 COPB1 COPG1 DOCK8 EXOC7 GOPC PARD6A PARD6B PFN1 PRKCI RAPGEF1 TRIP10 TRIP6 WASL
Entrez ID		11135	23433
HPRD ID		07303	05791
Ensembl ID		ENSG00000128283	ENSG00000119729
Uniprot IDs		Q00587	D6W5A7 P17081 V9HWD0
PDB IDs			2ATX
Enriched GO Terms of Interacting Partners?
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