DEF6 and PBXIP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		DEF6	PBXIP1
Description		DEF6 guanine nucleotide exchange factor	PBX homeobox interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Filopodium Perinuclear Region Of Cytoplasm	Nucleus Cytosol Microtubule Membrane
	Molecular Function	Protein Binding	Transcription Corepressor Activity Protein Binding
	Biological Process		Multicellular Organism Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity
Pathways
Drugs
Diseases
GWAS		Height ( 18391951) Systemic lupus erythematosus ( 28714469)	Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Inflammatory bowel disease ( 27569725) Prostate cancer ( 23535732)
Interacting Genes		15 interacting genes: APP BEGAIN CDC42 CDC42EP1 EIF4ENIF1 HOMEZ LCK PBXIP1 PLSCR1 PTK2 RAC1 RAC2 RHOA TCF4 ZAP70	22 interacting genes: BRPF1 CAPN2 CCDC85B CCNC DAXX DEF6 DPPA2 ESR1 GMCL1 GRB2 MDFI MDM2 MORF4L1 PCBD2 PRKAA2 SGTA TSNAX UBQLN1 UBQLN4 WASHC3 ZMYND8 ZZZ3
Entrez ID		50619	57326
HPRD ID		10869	17823
Ensembl ID		ENSG00000023892	ENSG00000163346
Uniprot IDs		Q9H4E7	B4E0K4 Q96AQ6
PDB IDs
Enriched GO Terms of Interacting Partners?
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