ABI1 and CYFIP2

Number of citations of the paper that reports this interaction (PubMedID 15048123)
134

Data Source:
HPRD (in vitro)

		ABI1	CYFIP2
Description		abl interactor 1	cytoplasmic FMR1 interacting protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Intracellular Nucleus Endoplasmic Reticulum Cytosol Cytoskeleton Plasma Membrane Postsynaptic Density Aggresome Lamellipodium Cell Junction Growth Cone SCAR Complex Filopodium Tip Extracellular Exosome	Nucleus Cytoplasm Cytosol Membrane Cell Junction SCAR Complex Neuron Projection Synapse Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding Protein Tyrosine Kinase Activator Activity Cadherin Binding	RNA 7-methylguanosine Cap Binding Protein Binding
	Biological Process	Somitogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Actin Polymerization Or Depolymerization Negative Regulation Of Cell Proliferation Viral Process Peptidyl-tyrosine Phosphorylation Megakaryocyte Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Vascular Endothelial Growth Factor Receptor Signaling Pathway Dendrite Morphogenesis Positive Regulation Of Protein Tyrosine Kinase Activity Lamellipodium Morphogenesis	Cell Morphogenesis Apoptotic Process Axon Guidance Cell Projection Assembly Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Proteolysis Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Neurotrophin TRK Receptor Signaling Pathway Activation Of Cysteine-type Endopeptidase Activity Dendrite Extension Cell-cell Adhesion
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS			Daytime sleep phenotypes ( 27126917) FEV1 ( 30804560) Gamma glutamyl transferase levels ( 29403010) Lung function (FEV1/FVC) ( 28166213 30804560) Peak expiratory flow ( 30804560)
Interacting Genes		29 interacting genes: ABL1 APBB1 CACNA1A CUL2 CYFIP2 ENAH EPS8 EPS8L1 EVL GAS7 HSPA8 MINK1 NCK1 NCK2 NCKAP1 NEB NIN PAK2 PCM1 PRPF40A SOS1 SOS2 SPTA1 SPTAN1 SRRM1 TCERG1 VASP WASF1 WASF2	22 interacting genes: ABI1 ABI3 APBB1 BIRC3 BRK1 DNMBP F2RL1 FMR1 FXR1 FXR2 GAS7 MTDH NCK1 NCKAP1 PLG PRPF40A SMAD4 TCERG1 WASF1 WASF2 YWHAG ZC3H12A
Entrez ID		10006	26999
HPRD ID		04336	07556
Ensembl ID		ENSG00000136754	ENSG00000055163
Uniprot IDs		A0A0A0MRT6 B6VEX3 B6VEX4 B6VEX5 Q8IZP0	B7Z8N7 E7EVJ5 Q96F07
PDB IDs
Enriched GO Terms of Interacting Partners?
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