PAEP and IGSF21

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PAEP	IGSF21
Description		progestagen associated endometrial protein	immunoglobin superfamily member 21
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Adherens Junction Anchored Component Of External Side Of Plasma Membrane Presynaptic Membrane Postsynaptic Membrane Inhibitory Synapse
	Molecular Function	Protein Binding Small Molecule Binding	Signaling Receptor Activity Protein Homodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Apoptotic Process Multicellular Organism Development Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production Negative Regulation Of Sperm Capacitation Regulation Of Binding Of Sperm To Zona Pellucida Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-6 Secretion	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Synapse Maturation
Pathways
Drugs		12-Bromododecanoic Acid Palmitic Acid Glycerin
Diseases
GWAS			Atypical femoral fracture in phosphonate treatment ( 31006051) Cobalt levels ( 26025379) Diabetic retinopathy ( 21441570) Erectile dysfunction and prostate cancer treatment ( 20932654) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Serum bilirubin levels x sex interaction in metabolic syndrome ( 30621171) Survival in pancreatic cancer ( 28470677)
Interacting Genes		13 interacting genes: A2M APP COPS6 EEF1A1 GRAMD2B IGSF21 LRIF1 PTPRC SMAD3 SUN2 TOR1A UBE2E1 XRCC6	32 interacting genes: ALDH2 ANXA3 ATF3 BCR BTBD2 CRCT1 DGKD EPB41L3 ERH ETHE1 GADD45A GIPC2 GSK3B GSTM4 HSPB1 KRAS MAD2L1BP NACA NREP PAEP PAFAH1B3 PCDHA4 PRMT1 PSMD11 RPP14 S100A8 SEPHS1 SERPINB9 SULT1E1 TMSB4X TRBV2 UBE2V2
Entrez ID		5047	84966
HPRD ID		01411	11309
Ensembl ID		ENSG00000122133	ENSG00000117154
Uniprot IDs		A0A024R8D8 A6XNE0 B2R4F9 B4E3C0 P09466	Q96ID5
PDB IDs		4R0B
Enriched GO Terms of Interacting Partners?
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