IGSF21 and GSTM4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		IGSF21	GSTM4
Description		immunoglobin superfamily member 21	glutathione S-transferase mu 4
Image		No pdb structure
GO Annotations	Cellular Component	Adherens Junction Anchored Component Of External Side Of Plasma Membrane Presynaptic Membrane Postsynaptic Membrane Inhibitory Synapse	Cytoplasm Cytosol Intercellular Bridge
	Molecular Function	Signaling Receptor Activity Protein Homodimerization Activity Cell Adhesion Molecule Binding	Glutathione Transferase Activity Protein Binding Enzyme Binding Protein Homodimerization Activity Glutathione Binding
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Synapse Maturation	Glutathione Metabolic Process Nitrobenzene Metabolic Process Xenobiotic Catabolic Process Long-chain Fatty Acid Biosynthetic Process Glutathione Derivative Biosynthetic Process
Pathways			Glutathione conjugation Biosynthesis of maresin conjugates in tissue regeneration (MCTR)
Drugs			Glutathione Glutathione Sulfonic Acid S-Octylglutathione Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine 1-Hydroxy-2-S-Glutathionyl-3-Para-Nitrophenoxy-Propane S-Hexylglutathione
Diseases
GWAS		Atypical femoral fracture in phosphonate treatment ( 31006051) Cobalt levels ( 26025379) Diabetic retinopathy ( 21441570) Erectile dysfunction and prostate cancer treatment ( 20932654) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Serum bilirubin levels x sex interaction in metabolic syndrome ( 30621171) Survival in pancreatic cancer ( 28470677)	Seasonality and depression ( 30217971)
Interacting Genes		32 interacting genes: ALDH2 ANXA3 ATF3 BCR BTBD2 CRCT1 DGKD EPB41L3 ERH ETHE1 GADD45A GIPC2 GSK3B GSTM4 HSPB1 KRAS MAD2L1BP NACA NREP PAEP PAFAH1B3 PCDHA4 PRMT1 PSMD11 RPP14 S100A8 SEPHS1 SERPINB9 SULT1E1 TMSB4X TRBV2 UBE2V2	10 interacting genes: APLP1 GSTM3 IGSF21 LRIF1 MED31 NELFCD TLE1 TP53 UNC119 ZBTB16
Entrez ID		84966	2948
HPRD ID		11309	00706
Ensembl ID		ENSG00000117154	ENSG00000168765
Uniprot IDs		Q96ID5	A0A140VKE3 Q03013
PDB IDs			4GTU
Enriched GO Terms of Interacting Partners?
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