PAEP and A2M

Number of citations of the paper that reports this interaction (PubMedID 11023837)
0

Data Source:
HPRD (in vitro)

		PAEP	A2M
Description		progestagen associated endometrial protein	alpha-2-macroglobulin
Image
GO Annotations	Cellular Component	Extracellular Region	Extracellular Region Extracellular Space Cytosol Platelet Alpha Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	Protein Binding Small Molecule Binding	Protease Binding Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Signaling Receptor Binding Protein Binding Growth Factor Binding Enzyme Binding Interleukin-8 Binding Interleukin-1 Binding Tumor Necrosis Factor Binding Calcium-dependent Protein Binding
	Biological Process	Apoptotic Process Multicellular Organism Development Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production Negative Regulation Of Sperm Capacitation Regulation Of Binding Of Sperm To Zona Pellucida Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-6 Secretion	Negative Regulation Of Complement Activation, Lectin Pathway Platelet Degranulation Blood Coagulation, Intrinsic Pathway Negative Regulation Of Endopeptidase Activity Extracellular Matrix Disassembly Stem Cell Differentiation Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Platelet degranulation Intrinsic Pathway of Fibrin Clot Formation Degradation of the extracellular matrix Rho GTPase cycle HDL assembly
Drugs		12-Bromododecanoic Acid Palmitic Acid Glycerin	Becaplermin Cisplatin Bacitracin Zinc Ocriplasmin
Diseases
GWAS
Interacting Genes		13 interacting genes: A2M APP COPS6 EEF1A1 GRAMD2B IGSF21 LRIF1 PTPRC SMAD3 SUN2 TOR1A UBE2E1 XRCC6	94 interacting genes: ACTB ADAM19 ADAMTS1 AMBP ANXA6 ANXA7 AP1M2 APOE APP ATF7IP ATP1A1 B2M C11orf58 CDC37 CDC42 CDK2AP2 CDKN1A CELA1 CPB2 CTSB CTSE CYP2C18 CYP2C8 DNAJB1 ECSIT EGLN2 ELAVL3 ENO2 EVI5L EXOSC1 FARSA FBXL12 FBXW4 FIS1 GCDH GEM GRB2 H2AX HMOX2 HSPA5 HSPB2 IFIT3 IFIT5 IGSF8 IL10 IL1B IL4 KLK13 KLK2 KLK3 LCAT LEP LONP1 LRP1 LYZ MAST1 MLST8 MMP2 MYOC NCDN NGF NOS3 NUDT21 OGA PAEP PAXIP1 PDGFA PDGFB PRAM1 PRDX2 RAB3A RAD23A RAP1B RETN RHEB RNF32 RPP14 SEPTIN8 SHBG SMN1 STAMBPL1 SWSAP1 TGFBI TGIF1 TGM2 TK1 TNFRSF14 TRAPPC5 TSC22D1 TTR TUBA1B TYRO3 UFD1 UMPS
Entrez ID		5047	2
HPRD ID		01411	00072
Ensembl ID		ENSG00000122133	ENSG00000175899
Uniprot IDs		A0A024R8D8 A6XNE0 B2R4F9 B4E3C0 P09466	P01023
PDB IDs		4R0B	1BV8 2P9R 4ACQ
Enriched GO Terms of Interacting Partners?
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