MOS and CCDC136

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MOS	CCDC136
Description		MOS proto-oncogene, serine/threonine kinase	coiled-coil domain containing 136
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Cytosol	Acrosomal Membrane Integral Component Of Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding
	Biological Process	MAPK Cascade Activation Of MAPKK Activity Activation Of MAPK Activity Meiotic Spindle Organization Chromatin Organization Positive Regulation Of MAPK Cascade Protein Autophosphorylation Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle	Acrosome Assembly Spermatogenesis Single Fertilization
Pathways
Drugs
Diseases
GWAS		Height ( 18391951)	Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		29 interacting genes: ACTN2 ATRIP BMPR2 BORCS6 CALCOCO2 CBY2 CCDC102B CCDC136 CCDC33 CCNDBP1 DYDC1 GFAP GOLGA2 HOMER3 HSPA1A KIFC3 KRT13 KRT15 KRT40 LZTS2 MID2 MTMR9 MYOD1 RHOU SEC24C SSX2IP TRAF1 TRIM27 USHBP1	64 interacting genes: ABT1 AQP1 ATP5PO ATXN1 BARD1 BLOC1S6 BYSL C1orf216 CBX8 CCDC146 CCHCR1 CDC5L CDK2AP1 CEP57L1 COIL CWF19L2 DISC1 ENKD1 FAM107A FAM161A GFI1B HAUS1 HDAC4 HGS HMG20A HMG20B JMY KANSL1 KAT5 KIFC3 LENG1 MAGEB4 MOS NDN NEBL PDLIM5 PKN2 PPP1R18 PRPF31 PSMD9 RAB33A SHFL SMARCE1 TBRG1 TCEA2 TNNT1 TXLNA UBQLN4 USP2 WT1 ZBTB38 ZC2HC1C ZNF20 ZNF230 ZNF250 ZNF408 ZNF417 ZNF490 ZNF564 ZNF572 ZNF581 ZNF587 ZNF688 ZSCAN26
Entrez ID		4342	64753
HPRD ID		01816	10887
Ensembl ID		ENSG00000172680	ENSG00000128596
Uniprot IDs		P00540	A0A024R758 Q96JN2
PDB IDs
Enriched GO Terms of Interacting Partners?
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