CCDC136 and TNNT1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCDC136	TNNT1
Description		coiled-coil domain containing 136	troponin T1, slow skeletal type
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Membrane Integral Component Of Membrane	Cytosol Troponin Complex
	Molecular Function		Calcium Ion Binding Protein Binding Tropomyosin Binding Calcium-dependent ATPase Activity Troponin T Binding
	Biological Process	Acrosome Assembly Spermatogenesis Single Fertilization	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Muscle Filament Sliding Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction Cardiac Muscle Contraction
Pathways			Striated Muscle Contraction
Drugs
Diseases			Nemaline myopathy
GWAS		Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)	Height ( 31562340)
Interacting Genes		64 interacting genes: ABT1 AQP1 ATP5PO ATXN1 BARD1 BLOC1S6 BYSL C1orf216 CBX8 CCDC146 CCHCR1 CDC5L CDK2AP1 CEP57L1 COIL CWF19L2 DISC1 ENKD1 FAM107A FAM161A GFI1B HAUS1 HDAC4 HGS HMG20A HMG20B JMY KANSL1 KAT5 KIFC3 LENG1 MAGEB4 MOS NDN NEBL PDLIM5 PKN2 PPP1R18 PRPF31 PSMD9 RAB33A SHFL SMARCE1 TBRG1 TCEA2 TNNT1 TXLNA UBQLN4 USP2 WT1 ZBTB38 ZC2HC1C ZNF20 ZNF230 ZNF250 ZNF408 ZNF417 ZNF490 ZNF564 ZNF572 ZNF581 ZNF587 ZNF688 ZSCAN26	61 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT40 LARP1 LDOC1 MARS1 MORF4L1 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TPM1 TPM3 TRA2A TRIM63 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768
Entrez ID		64753	7138
HPRD ID		10887	01841
Ensembl ID		ENSG00000128596	ENSG00000105048
Uniprot IDs		A0A024R758 Q96JN2	P13805
PDB IDs
Enriched GO Terms of Interacting Partners?
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