CCDC136 and ZBTB38

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCDC136	ZBTB38
Description		coiled-coil domain containing 136	zinc finger and BTB domain containing 38
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Chromosome Blood Microparticle
	Molecular Function		DNA Binding DNA-binding Transcription Factor Activity Protein Binding Methyl-CpG Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Acrosome Assembly Spermatogenesis Single Fertilization	Regulation Of DNA Replication Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)	Advanced glycation end-product levels ( 26915486) Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Blond vs. brown/black hair color ( 30531825) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Breast cancer ( 29059683) Brown vs. black hair color ( 30531825) Chronic obstructive pulmonary disease ( 30804561) Crohn's disease ( 28067908) Diastolic blood pressure ( 27618447) Estimated glomerular filtration rate ( 31152163) Hair color ( 29662168) Heel bone mineral density ( 30598549) Height ( 21998595 28552196 20881960 25282103 25429064 19396169 19343178 19893584 23563607 31562340 28270201 18391950 18391951 18391952 18193045 20189936) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 25673412) Infant length ( 25281659) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 27863252) Male-pattern baldness ( 28196072) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244 24076602) Myopia ( 27182965) Non-albumin protein levels ( 29403010) Offspring birth weight ( 31043758) Prion diseases ( 22210626) Prostate cancer ( 21743467) Prostate-specific antigen levels (conditioned on lead SNPs) ( 28139693) Pulmonary function in asthmatics ( 25221879) Red blood cell count ( 27863252) Serum total protein level ( 29403010) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure ( 27618447) Waist circumference ( 25673412) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in inactive individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for BMI in smokers ( 28443625) Waist circumference adjusted for body mass index ( 28552196 25673412 28448500) Weight ( 28552196)
Interacting Genes		64 interacting genes: ABT1 AQP1 ATP5PO ATXN1 BARD1 BLOC1S6 BYSL C1orf216 CBX8 CCDC146 CCHCR1 CDC5L CDK2AP1 CEP57L1 COIL CWF19L2 DISC1 ENKD1 FAM107A FAM161A GFI1B HAUS1 HDAC4 HGS HMG20A HMG20B JMY KANSL1 KAT5 KIFC3 LENG1 MAGEB4 MOS NDN NEBL PDLIM5 PKN2 PPP1R18 PRPF31 PSMD9 RAB33A SHFL SMARCE1 TBRG1 TCEA2 TNNT1 TXLNA UBQLN4 USP2 WT1 ZBTB38 ZC2HC1C ZNF20 ZNF230 ZNF250 ZNF408 ZNF417 ZNF490 ZNF564 ZNF572 ZNF581 ZNF587 ZNF688 ZSCAN26	14 interacting genes: CBFA2T3 CCDC136 EHMT2 FSD2 KRT40 KRTAP10-7 KRTAP10-9 LZTS2 MTUS2 PDE4DIP RALBP1 RBBP6 TRIM41 TSGA10
Entrez ID		64753	253461
HPRD ID		10887	10985
Ensembl ID		ENSG00000128596	ENSG00000177311
Uniprot IDs		A0A024R758 Q96JN2	Q8NAP3 Q9H6F0
PDB IDs			6E93 6E94
Enriched GO Terms of Interacting Partners?
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