CCDC136 and HMG20B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCDC136	HMG20B
Description		coiled-coil domain containing 136	high mobility group 20B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Chromosome Nuclear Body
	Molecular Function		DNA Binding Protein Binding
	Biological Process	Acrosome Assembly Spermatogenesis Single Fertilization	Chromatin Organization Cell Cycle Blood Coagulation Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation
Pathways			HDACs deacetylate histones Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		64 interacting genes: ABT1 AQP1 ATP5PO ATXN1 BARD1 BLOC1S6 BYSL C1orf216 CBX8 CCDC146 CCHCR1 CDC5L CDK2AP1 CEP57L1 COIL CWF19L2 DISC1 ENKD1 FAM107A FAM161A GFI1B HAUS1 HDAC4 HGS HMG20A HMG20B JMY KANSL1 KAT5 KIFC3 LENG1 MAGEB4 MOS NDN NEBL PDLIM5 PKN2 PPP1R18 PRPF31 PSMD9 RAB33A SHFL SMARCE1 TBRG1 TCEA2 TNNT1 TXLNA UBQLN4 USP2 WT1 ZBTB38 ZC2HC1C ZNF20 ZNF230 ZNF250 ZNF408 ZNF417 ZNF490 ZNF564 ZNF572 ZNF581 ZNF587 ZNF688 ZSCAN26	20 interacting genes: APP BRCA2 CCDC102B CCDC136 CCDC85B E2F6 FBXO7 HMG20A HNRNPL KIF4A KRT15 KRT38 MID1 NKX3-1 PHF21A SYCE1 TACC2 TFIP11 TRAF1 VIM
Entrez ID		64753	10362
HPRD ID		10887	05703
Ensembl ID		ENSG00000128596	ENSG00000064961
Uniprot IDs		A0A024R758 Q96JN2	Q9P0W2
PDB IDs
Enriched GO Terms of Interacting Partners?
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