IL16 and PPP1R12B

Number of citations of the paper that reports this interaction (PubMedID 12923170)
11

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		IL16	PPP1R12B
Description		interleukin 16	protein phosphatase 1 regulatory subunit 12B
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytosol Plasma Membrane Nuclear Speck Flemming Body	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Z Disc A Band
	Molecular Function	Cytokine Activity CD4 Receptor Binding	Enzyme Inhibitor Activity Protein Binding Enzyme Activator Activity Phosphatase Regulator Activity Protein Kinase Binding
	Biological Process	Immune Response Viral Process Cytokine-mediated Signaling Pathway Leukocyte Chemotaxis Induction Of Positive Chemotaxis Regulation Of Calcium Ion Transport	G2/M Transition Of Mitotic Cell Cycle Regulation Of Muscle Contraction Signal Transduction Positive Regulation Of Catalytic Activity Negative Regulation Of Catalytic Activity
Pathways		Other interleukin signaling	RHO GTPases activate PKNs RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Blood protein levels in cardiovascular risk ( 28369058) Body mass index ( 26426971) Brown vs. black hair color ( 30531825) Colorectal cancer (aspirin and/or NSAID use interaction) ( 25781442) Height ( 31562340) Inattentive symptoms ( 18821565) Interleukin-16 levels ( 27989323) Primary biliary cholangitis ( 28425483)	Celiac disease ( 23936387) Coronary heart disease ( 24778558) Obesity-related traits ( 23251661) Sex ratio ( 26763874)
Interacting Genes		31 interacting genes: CASP3 CD4 CDK1 CSNK2A1 CSNK2A2 DMRTB1 EFEMP2 GABPB1 GRIN2A GRIN2B GRIN2C GRIN2D HDAC3 KCNA3 KCND1 KCND2 KCNJ10 KCNJ15 KCNJ2 KCNJ4 KDM1A LNX2 PCSK6 PPP1R12A PPP1R12B PPP1R12C SUV39H1 TFIP11 TRIP6 USHBP1 ZNRD2	3 interacting genes: IL16 PPP1CB PRKG1
Entrez ID		3603	4660
HPRD ID		04329	04794
Ensembl ID		ENSG00000172349	ENSG00000077157
Uniprot IDs		Q14005 Q9UME6	E1CKY7 O60237
PDB IDs		1I16 1X6D 5FB8
Enriched GO Terms of Interacting Partners?
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