IL16 and KCNJ10

Number of citations of the paper that reports this interaction (PubMedID 10479680)
20

Data Source:
HPRD (two hybrid, in vitro)

		IL16	KCNJ10
Description		interleukin 16	potassium inwardly rectifying channel subfamily J member 10
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytosol Plasma Membrane Nuclear Speck Flemming Body	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Presynapse
	Molecular Function	Cytokine Activity CD4 Receptor Binding	Inward Rectifier Potassium Channel Activity Protein Binding ATP Binding ATP-activated Inward Rectifier Potassium Channel Activity
	Biological Process	Immune Response Viral Process Cytokine-mediated Signaling Pathway Leukocyte Chemotaxis Induction Of Positive Chemotaxis Regulation Of Calcium Ion Transport	Potassium Ion Transport Visual Perception Adult Walking Behavior Central Nervous System Myelination Regulation Of Ion Transmembrane Transport Regulation Of Long-term Neuronal Synaptic Plasticity Glutamate Reuptake Potassium Ion Homeostasis Regulation Of Resting Membrane Potential Potassium Ion Import Across Plasma Membrane
Pathways		Other interleukin signaling	Activation of G protein gated Potassium channels Potassium transport channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Yohimbine
Diseases			Seizures-sensorineural deafness-ataxia-mental retardation-electrolyte imbalance (SESAME) ; SeSAME/EAST syndrome
GWAS		Blood protein levels ( 30072576 29875488 28240269) Blood protein levels in cardiovascular risk ( 28369058) Body mass index ( 26426971) Brown vs. black hair color ( 30531825) Colorectal cancer (aspirin and/or NSAID use interaction) ( 25781442) Height ( 31562340) Inattentive symptoms ( 18821565) Interleukin-16 levels ( 27989323) Primary biliary cholangitis ( 28425483)
Interacting Genes		31 interacting genes: CASP3 CD4 CDK1 CSNK2A1 CSNK2A2 DMRTB1 EFEMP2 GABPB1 GRIN2A GRIN2B GRIN2C GRIN2D HDAC3 KCNA3 KCND1 KCND2 KCNJ10 KCNJ15 KCNJ2 KCNJ4 KDM1A LNX2 PCSK6 PPP1R12A PPP1R12B PPP1R12C SUV39H1 TFIP11 TRIP6 USHBP1 ZNRD2	8 interacting genes: APP DLG1 DLG4 IL16 KCNJ16 PATJ SIAH1 SNTA1
Entrez ID		3603	3766
HPRD ID		04329	03732
Ensembl ID		ENSG00000172349	ENSG00000177807
Uniprot IDs		Q14005 Q9UME6	P78508
PDB IDs		1I16 1X6D 5FB8
Enriched GO Terms of Interacting Partners?
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