IL16 and PCSK6

		IL16	PCSK6
Description		interleukin 16	proprotein convertase subtilisin/kexin type 6
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytosol Plasma Membrane Nuclear Speck Flemming Body	Extracellular Region Extracellular Space Endoplasmic Reticulum Golgi Lumen Plasma Membrane Cell Surface Membrane Collagen-containing Extracellular Matrix
	Molecular Function	Cytokine Activity CD4 Receptor Binding	Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Heparin Binding Nerve Growth Factor Binding
	Biological Process	Immune Response Viral Process Cytokine-mediated Signaling Pathway Leukocyte Chemotaxis Induction Of Positive Chemotaxis Regulation Of Calcium Ion Transport	Zygotic Determination Of Anterior/posterior Axis, Embryo Determination Of Left/right Symmetry Glycoprotein Metabolic Process Protein Processing Peptide Hormone Processing Regulation Of BMP Signaling Pathway Nerve Growth Factor Processing Nerve Growth Factor Production Secretion By Cell Regulation Of Lipoprotein Lipase Activity Cornification
Pathways		Other interleukin signaling	Signaling by NODAL NGF processing Formation of the cornified envelope Assembly of active LPL and LIPC lipase complexes
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Blood protein levels in cardiovascular risk ( 28369058) Body mass index ( 26426971) Brown vs. black hair color ( 30531825) Colorectal cancer (aspirin and/or NSAID use interaction) ( 25781442) Height ( 31562340) Inattentive symptoms ( 18821565) Interleukin-16 levels ( 27989323) Primary biliary cholangitis ( 28425483)	Cytokine levels ( 31679650) Cytokine network levels (multivariate analysis) ( 31679650) Handedness in dyslexia ( 21051773) Height ( 31562340) Platelet-derived growth factor BB levels ( 27989323) Relative hand skill in reading disability ( 24068947) Triglycerides ( 30275531) Tuberculosis ( 30713548) Type 2 diabetes ( 30470734)
Interacting Genes		31 interacting genes: CASP3 CD4 CDK1 CSNK2A1 CSNK2A2 DMRTB1 EFEMP2 GABPB1 GRIN2A GRIN2B GRIN2C GRIN2D HDAC3 KCNA3 KCND1 KCND2 KCNJ10 KCNJ15 KCNJ2 KCNJ4 KDM1A LNX2 PCSK6 PPP1R12A PPP1R12B PPP1R12C SUV39H1 TFIP11 TRIP6 USHBP1 ZNRD2	10 interacting genes: ALPL CACNA1A FLG FN3K IGF1R IL16 PMCH RCN3 SNRPA1 SYNM
Entrez ID		3603	5046
HPRD ID		04329	01329
Ensembl ID		ENSG00000172349	ENSG00000140479
Uniprot IDs		Q14005 Q9UME6	A2RQD9 H7BXT3 P29122 Q59H04
PDB IDs		1I16 1X6D 5FB8
Enriched GO Terms of Interacting Partners?
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