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AQP1 and CCDC136
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
381
Data Source:
BioGRID
(two hybrid)
AQP1
CCDC136
Description
aquaporin 1 (Colton blood group)
coiled-coil domain containing 136
Image
No pdb structure
GO Annotations
Cellular Component
Cell
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Symbiont-containing Vacuole
Symbiont-containing Vacuole Membrane
Brush Border Membrane
Nuclear Membrane
Sarcolemma
Apical Part Of Cell
Extracellular Exosome
Acrosomal Membrane
Integral Component Of Membrane
Molecular Function
Intracellular CGMP-activated Cation Channel Activity
Potassium Channel Activity
Water Transmembrane Transporter Activity
Protein Binding
Ammonium Transmembrane Transporter Activity
Potassium Ion Transmembrane Transporter Activity
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Transmembrane Transporter Activity
Nitric Oxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transporter Activity
Identical Protein Binding
Biological Process
Renal Water Homeostasis
Renal Water Transport
Potassium Ion Transport
Water Transport
Cell Volume Homeostasis
Hyperosmotic Response
Cellular Water Homeostasis
Carbon Dioxide Transport
Ammonium Transport
Bicarbonate Transport
Glycerol Transport
Cellular Homeostasis
CGMP-mediated Signaling
Lateral Ventricle Development
Pancreatic Juice Secretion
Nitric Oxide Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Cerebrospinal Fluid Secretion
Cellular Response To UV
Transepithelial Water Transport
Carbon Dioxide Transmembrane Transport
Odontogenesis
Response To Drug
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of Saliva Secretion
Positive Regulation Of Fibroblast Proliferation
Multicellular Organismal Water Homeostasis
Cellular Response To Hydrogen Peroxide
Cellular Response To Inorganic Substance
Cellular Response To Mechanical Stimulus
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Cellular Response To Retinoic Acid
Cellular Response To CAMP
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Hyperosmotic Response
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Potassium Ion Transmembrane Transport
Ammonium Transmembrane Transport
Maintenance Of Symbiont-containing Vacuole By Host
Acrosome Assembly
Spermatogenesis
Single Fertilization
Pathways
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Drugs
Acetazolamide
Diseases
GWAS
Fractures (
30598549
)
Heel bone mineral density (
30598549
28869591
)
Huntington's disease progression (
28642124
)
Kidney stones (
31729369
)
Nephrolithiasis (
22396660
)
Systolic blood pressure (
30224653
)
Total body bone mineral density (
29304378
)
Reading disability or specific language impairment (pleiotropy) (
25065397
)
Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) (
25065397
)
Interacting Genes
44 interacting genes:
ADAMTSL4
CCDC136
CCDC57
CCDC85B
CEP44
CREB3
CRTAC1
CSRNP1
EFEMP2
EPHB2
FOS
FSD2
IHO1
IKZF2
IKZF3
KCTD17
KCTD9
KIAA1958
KRT31
KRT33B
KRT40
KRTAP10-3
KRTAP10-7
KRTAP4-12
KRTAP4-2
KRTAP9-2
LMNA
MDFI
MID2
MTUS2
NBPF22P
NOTCH2NLA
PICK1
RGS17
RGS20
RIMBP3
SIAH1
SPRY2
TCF4
TNK2
TRAF1
TRAF2
TRIM23
TRIP6
64 interacting genes:
ABT1
AQP1
ATP5PO
ATXN1
BARD1
BLOC1S6
BYSL
C1orf216
CBX8
CCDC146
CCHCR1
CDC5L
CDK2AP1
CEP57L1
COIL
CWF19L2
DISC1
ENKD1
FAM107A
FAM161A
GFI1B
HAUS1
HDAC4
HGS
HMG20A
HMG20B
JMY
KANSL1
KAT5
KIFC3
LENG1
MAGEB4
MOS
NDN
NEBL
PDLIM5
PKN2
PPP1R18
PRPF31
PSMD9
RAB33A
SHFL
SMARCE1
TBRG1
TCEA2
TNNT1
TXLNA
UBQLN4
USP2
WT1
ZBTB38
ZC2HC1C
ZNF20
ZNF230
ZNF250
ZNF408
ZNF417
ZNF490
ZNF564
ZNF572
ZNF581
ZNF587
ZNF688
ZSCAN26
Entrez ID
358
64753
HPRD ID
00140
10887
Ensembl ID
ENSG00000240583
ENSG00000128596
Uniprot IDs
A0A024RA31
P29972
A0A024R758
Q96JN2
PDB IDs
1FQY
1H6I
1IH5
4CSK
6POJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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