NCAPH2 and EGLN3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		NCAPH2	EGLN3
Description		non-SMC condensin II complex subunit H2	egl-9 family hypoxia inducible factor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Condensin Complex Nucleus Nucleoplasm Membrane Cell Junction Intercellular Bridge	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Chromatin Binding Protein Binding	Iron Ion Binding Protein Binding Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, 2-oxoglutarate As One Donor, And Incorporation Of One Atom Each Of Oxygen Into Both Donors L-ascorbic Acid Binding Peptidyl-proline 4-dioxygenase Activity
	Biological Process	Mitotic Chromosome Condensation Meiotic Chromosome Condensation T Cell Differentiation In Thymus Chromosome Organization Mitotic Sister Chromatid Separation Female Meiosis Chromosome Separation	Response To Hypoxia Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To DNA Damage Stimulus Protein Hydroxylation Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Regulation Of Cell Proliferation Regulation Of Neuron Apoptotic Process Oxidation-reduction Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Pathways		Condensation of Prophase Chromosomes	Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Drugs			Vitamin C Roxadustat
Diseases
GWAS		B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Cerebrospinal fluid clusterin levels ( 26545630) Chronic lymphocytic leukemia ( 28165464) Mean corpuscular hemoglobin ( 20139978) Red blood cell traits ( 23222517)	Alzheimer's disease (late onset) ( 30820047) Daytime sleep phenotypes ( 27126917) Hematocrit ( 27863252)
Interacting Genes		11 interacting genes: ACTN2 EGLN3 FOLR1 LMO2 PRPF31 SNRPC TRAF2 TTC25 TTC32 TUBB USHBP1	25 interacting genes: ABI2 ADRB2 ATF4 EFHC2 EPAS1 EPOR FOXJ2 HIF1A HIF3A IKBKG MAPK1 MAPK7 NCAPH2 OS9 PKM PRPF19 SERTAD1 SIAH2 SRP54 SUMO1 SUMO2 SUMO3 TP53 TTC23L WDR83
Entrez ID		29781	112399
HPRD ID		11783	06972
Ensembl ID		ENSG00000025770	ENSG00000129521
Uniprot IDs		Q6IBW4	B3KVT0 F8W1G2 Q3T1B0 Q9H6Z9
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?