RBMX and SORBS3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		RBMX	SORBS3
Description		RNA binding motif protein X-linked	sorbin and SH3 domain containing 3
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Spliceosomal Complex Nuclear Euchromatin Membrane Protein-containing Complex Supraspliceosomal Complex Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex	Nucleus Cytosol Cytoskeleton Focal Adhesion
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Chromatin Binding RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Identical Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Transcription Factor Binding Vinculin Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Osteoblast Differentiation Transcription By RNA Polymerase II MRNA Splice Site Selection Membrane Protein Ectodomain Proteolysis RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Protein Homooligomerization Cellular Response To Interleukin-1	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Actin Filament Organization Cell Adhesion Cell-substrate Adhesion Positive Regulation Of MAPK Cascade Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Stress Fiber Assembly
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	Smooth Muscle Contraction
Drugs
Diseases
GWAS		Pediatric autoimmune diseases ( 26301688)	Diastolic blood pressure ( 30224653) HIV-1 viral setpoint ( 20205591) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Parkinson's disease ( 28892059)
Interacting Genes		37 interacting genes: APOBEC3C CCDC33 CIRBP CLK1 CLK3 CSNK2A1 FUS FXR2 HNRNPK IL7R ITSN2 JAK2 KHDRBS1 KHDRBS2 KHDRBS3 LNX1 MAGOHB NABP1 NFE2L2 PRPF31 PRR3 PSMF1 RAMAC RBM3 RBM7 RBMY1A1 RBMY1F ROBO3 SNRPA SOCS3 SORBS3 SREK1 SRPK2 STAT5A TRA2B XRN1 ZNF490	46 interacting genes: ABL1 ADAM15 ADAMTSL4 ARNT2 CBLB CPEB2 CPNE2 CPSF7 DDX17 DIP2A DLG5 DMRTB1 DVL2 EFS EIF3H FASLG FLOT1 HNRNPK HNRNPUL1 INPPL1 KIAA0408 KIAA1217 MAPK1 MAPK3 NCK1 NCKIPSD NOTCH3 PAK2 PAK5 RBMX SAFB2 SAXO1 SH2D4A SOCS7 SRCIN1 TBC1D22B TRIM23 TRIM27 TRIM41 VARS2 VPS37B VPS37C ZBED1 ZBTB25 ZBTB7B ZC4H2
Entrez ID		27316	10174
HPRD ID		02186	11535
Ensembl ID		ENSG00000147274	ENSG00000120896
Uniprot IDs		P38159	O60504
PDB IDs		2MB0 2MKS	2CT3 2DLM 2NWM 2YUP
Enriched GO Terms of Interacting Partners?
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