SHANK2 and DLGAP2

Number of citations of the paper that reports this interaction (PubMedID 10527873)
58

Data Source:
BioGRID (two hybrid)

		SHANK2	DLGAP2
Description		SH3 and multiple ankyrin repeat domains 2	DLG associated protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cellular_component Cytosol Neurofilament Plasma Membrane Ionotropic Glutamate Receptor Complex Postsynaptic Density Apical Plasma Membrane Cell Junction Dendrite Growth Cone Brush Border Membrane Neuron Projection Neuronal Cell Body Dendritic Spine Neuron Spine Postsynaptic Membrane Ciliary Membrane	Neurofilament Plasma Membrane Postsynaptic Density Cell Junction
	Molecular Function	Protein Binding SH3 Domain Binding Receptor Signaling Complex Scaffold Activity GKAP/Homer Scaffold Activity Ionotropic Glutamate Receptor Binding	Protein Binding
	Biological Process	Synapse Assembly Behavior Learning Adult Behavior Social Behavior Brain Morphogenesis Synaptic Growth At Neuromuscular Junction Positive Regulation Of Synaptic Transmission, Glutamatergic Long-term Synaptic Potentiation Long-term Synaptic Depression Dendritic Spine Morphogenesis Positive Regulation Of Dendritic Spine Development Vocalization Behavior Postsynaptic Density Assembly Regulation Of AMPA Receptor Activity Positive Regulation Of Excitatory Postsynaptic Potential	Neuron-neuron Synaptic Transmission
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Hip circumference ( 28552196) Late-onset Alzheimer's disease ( 27770636) Obesity-related traits ( 23251661) Response to fenofibrate (adiponectin levels) ( 23149075) Urate levels in obese individuals ( 25811787)	Bipolar disorder ( 31043756) End-stage renal disease ( 29885931) Eye morphology ( 29921221) Lung cancer ( 28604730) Menarche (age at onset) ( 23599027) Neuritic plaque ( 31497858) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive astigmatism ( 30306274) Triglycerides ( 24886709) White matter microstructure in first episode schizophrenia (right posterior cingulate cortex) ( 28924203)
Interacting Genes		16 interacting genes: ADGRB2 ADGRL1 ADGRL2 ARHGEF7 BAIAP2 CTTN DLG4 DLGAP1 DLGAP2 DLGAP3 DLGAP4 DNAJC19 DNM2 SHARPIN SLC9A3 SSTR2	13 interacting genes: ADRB1 DGCR6 DLG4 DLGAP1 GRK5 KRT40 KRTAP4-2 NLGN4X NOS1 SHANK2 SHANK3 SORBS2 TSPOAP1
Entrez ID		22941	9228
HPRD ID		04479	09258
Ensembl ID		ENSG00000162105	ENSG00000198010
Uniprot IDs		A0A590UJ45 A6NHU9 C0SPH0 Q9UPX8	A0A1B0GTN4
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?