DLGAP2 and NLGN4X

Number of citations of the paper that reports this interaction (PubMedID 11368788)
47

Data Source:
HPRD (in vitro)

		DLGAP2	NLGN4X
Description		DLG associated protein 2	neuroligin 4 X-linked
Image		No pdb structure
GO Annotations	Cellular Component	Neurofilament Plasma Membrane Postsynaptic Density Cell Junction	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Integral Component Of Membrane Cell Junction Dendrite Synapse Excitatory Synapse Spanning Component Of Membrane Presynapse Postsynaptic Density Membrane Symmetric, GABA-ergic, Inhibitory Synapse Asymmetric, Glutamatergic, Excitatory Synapse
	Molecular Function	Protein Binding	Protein Binding Chloride Ion Binding Signaling Receptor Activity Neurexin Family Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding Scaffold Protein Binding
	Biological Process	Neuron-neuron Synaptic Transmission	Brainstem Development Neuron Cell-cell Adhesion Chemical Synaptic Transmission Learning Cerebellum Development Neuron Differentiation Adult Behavior Social Behavior Organ Growth Cell-cell Junction Organization Synaptic Vesicle Endocytosis Modulation Of Chemical Synaptic Transmission Synapse Organization Vocalization Behavior Negative Regulation Of Excitatory Postsynaptic Potential Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Presynapse Assembly
Pathways			Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases			Non-syndromic X-linked mental retardation
GWAS		Bipolar disorder ( 31043756) End-stage renal disease ( 29885931) Eye morphology ( 29921221) Lung cancer ( 28604730) Menarche (age at onset) ( 23599027) Neuritic plaque ( 31497858) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive astigmatism ( 30306274) Triglycerides ( 24886709) White matter microstructure in first episode schizophrenia (right posterior cingulate cortex) ( 28924203)	Metabolite levels ( 23823483) Schizophrenia ( 25056061 29483656)
Interacting Genes		13 interacting genes: ADRB1 DGCR6 DLG4 DLGAP1 GRK5 KRT40 KRTAP4-2 NLGN4X NOS1 SHANK2 SHANK3 SORBS2 TSPOAP1	2 interacting genes: DLG4 DLGAP2
Entrez ID		9228	57502
HPRD ID		09258	02336
Ensembl ID		ENSG00000198010	ENSG00000146938
Uniprot IDs		A0A1B0GTN4	A0A024RBV0 A8K4S1 B3KP11 Q8N0W4
PDB IDs			2WQZ 2XB6 3BE8
Enriched GO Terms of Interacting Partners?
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