SHANK2 and DLGAP4

Number of citations of the paper that reports this interaction (PubMedID 10527873)
58

Data Source:
BioGRID (two hybrid)

		SHANK2	DLGAP4
Description		SH3 and multiple ankyrin repeat domains 2	DLG associated protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Cellular_component Cytosol Neurofilament Plasma Membrane Ionotropic Glutamate Receptor Complex Postsynaptic Density Apical Plasma Membrane Cell Junction Dendrite Growth Cone Brush Border Membrane Neuron Projection Neuronal Cell Body Dendritic Spine Neuron Spine Postsynaptic Membrane Ciliary Membrane	Plasma Membrane Neuromuscular Junction Glutamatergic Synapse Cholinergic Synapse Postsynaptic Specialization
	Molecular Function	Protein Binding SH3 Domain Binding Receptor Signaling Complex Scaffold Activity GKAP/Homer Scaffold Activity Ionotropic Glutamate Receptor Binding	Protein Binding
	Biological Process	Synapse Assembly Behavior Learning Adult Behavior Social Behavior Brain Morphogenesis Synaptic Growth At Neuromuscular Junction Positive Regulation Of Synaptic Transmission, Glutamatergic Long-term Synaptic Potentiation Long-term Synaptic Depression Dendritic Spine Morphogenesis Positive Regulation Of Dendritic Spine Development Vocalization Behavior Postsynaptic Density Assembly Regulation Of AMPA Receptor Activity Positive Regulation Of Excitatory Postsynaptic Potential	Signaling
Pathways		Neurexins and neuroligins Neurexins and neuroligins	Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Hip circumference ( 28552196) Late-onset Alzheimer's disease ( 27770636) Obesity-related traits ( 23251661) Response to fenofibrate (adiponectin levels) ( 23149075) Urate levels in obese individuals ( 25811787)
Interacting Genes		16 interacting genes: ADGRB2 ADGRL1 ADGRL2 ARHGEF7 BAIAP2 CTTN DLG4 DLGAP1 DLGAP2 DLGAP3 DLGAP4 DNAJC19 DNM2 SHARPIN SLC9A3 SSTR2	15 interacting genes: BIN1 DLG1 DLG3 DLG4 EXOC4 GRIN1 GRIN2D PLP2 PPP1R1B SH3GL2 SHANK2 SHANK3 SORBS2 SYNGAP1 UBC
Entrez ID		22941	22839
HPRD ID		04479	16826
Ensembl ID		ENSG00000162105	ENSG00000080845
Uniprot IDs		A0A590UJ45 A6NHU9 C0SPH0 Q9UPX8	A0A0B4J2C2 Q9Y2H0
PDB IDs
Enriched GO Terms of Interacting Partners?
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