DLGAP4 and EXOC4

Number of citations of the paper that reports this interaction (PubMedID 12675619)
13

Data Source:
HPRD (in vitro, in vivo)

		DLGAP4	EXOC4
Description		DLG associated protein 4	exocyst complex component 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Neuromuscular Junction Glutamatergic Synapse Cholinergic Synapse Postsynaptic Specialization	Exocyst Cell Cytoplasm Cytosol Plasma Membrane Microvillus Membrane Growth Cone Membrane Myelin Sheath Abaxonal Region Synapse Flemming Body
	Molecular Function	Protein Binding	Protein Binding Ral GTPase Binding PDZ Domain Binding Protein N-terminus Binding
	Biological Process	Signaling	Protein Targeting To Membrane Exocytosis Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Chemical Synaptic Transmission Regulation Of Macroautophagy Paraxial Mesoderm Formation Vesicle Tethering Involved In Exocytosis
Pathways		Neurexins and neuroligins Neurexins and neuroligins	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS			Alzheimer's disease (cognitive decline) ( 23535033) Chronotype ( 30696823) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Extremely high intelligence ( 29520040) Food allergy ( 29030101) General cognitive ability ( 29844566) Household income (MTAG) ( 31844048) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Moderate to vigorous physical activity levels ( 29899525) Mood instability ( 31168069) Peanut allergy ( 29030101) Plasma anti-thyroid peroxidase levels ( 29678681) QT interval ( 29213071) Response to selective serotonin reuptake inhibitors in depression ( 30034349) Tonometry ( 17903302) Vigorous physical activity ( 29899525)
Interacting Genes		15 interacting genes: BIN1 DLG1 DLG3 DLG4 EXOC4 GRIN1 GRIN2D PLP2 PPP1R1B SH3GL2 SHANK2 SHANK3 SORBS2 SYNGAP1 UBC	9 interacting genes: BIRC6 CEP63 DISC1 DLG3 DLG4 DLGAP4 EXOC7 GRIN2B RALA
Entrez ID		22839	60412
HPRD ID		16826	12185
Ensembl ID		ENSG00000080845	ENSG00000131558
Uniprot IDs		A0A0B4J2C2 Q9Y2H0	Q6NX51 Q96A65
PDB IDs
Enriched GO Terms of Interacting Partners?
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