MAPRE3 and LMO2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MAPRE3	LMO2
Description		microtubule associated protein RP/EB family member 3	LIM domain only 2
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GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Microtubule Midbody Microtubule Plus-end Spindle Midzone Mitotic Spindle Astral Microtubule End	Nucleoplasm Transcription Factor Complex
	Molecular Function	Protein Binding Microtubule Binding Protein C-terminus Binding Protein Kinase Binding Identical Protein Binding Microtubule Plus-end Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding BHLH Transcription Factor Binding Metal Ion Binding Cofactor Binding E-box Binding
	Biological Process	Protein Localization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule Polymerization Protein Localization To Microtubule Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Transcription, DNA-templated Spindle Assembly Cell Division Positive Regulation Of Microtubule Plus-end Binding Protein Localization To Microtubule Plus-end	Multicellular Organism Development MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Thyroid Hormone Stimulus Regulation Of Hematopoietic Stem Cell Differentiation
Pathways			RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Diseases			Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708) Post bronchodilator FEV1/FVC ratio ( 26634245)	Cognitive performance ( 19734545) Iron status biomarkers (transferrin saturation) ( 28334935) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red blood cell count ( 27863252)
Interacting Genes		22 interacting genes: APC2 AURKA AURKB CLASP1 DCTN2 DOK4 EIF4E2 FXR2 GTSE1 JUN KIF19 LMO2 MAPRE1 MAPRE2 PSMA1 PSMB1 RAB1A SDCBP SIAH1 SLAIN1 TROAP TXN2	97 interacting genes: ABI2 ADAMTSL4 AFDN AGTRAP AIMP2 ALDH6A1 AXIN1 BANP BEX2 BLZF1 C1orf94 CALCOCO2 CBY2 CCDC33 CDC25A CDC5L CDX4 CLHC1 CMTM5 CORO1A CORO1C DAZAP2 DBF4B DDIT3 DRAP1 EHMT2 ELF2 ERBIN FHL3 GATA1 GATA2 GATA3 GFAP GOLGA2 GRB2 HNRNPC HNRNPM HOOK1 IFT43 IHO1 IKZF3 ISL1 KANK2 KDM5A KIF3B KRT15 KRT40 KRTAP10-7 LDB1 LYL1 LZTS2 MAGEA8 MAPRE1 MAPRE2 MAPRE3 MBIP MRFAP1L1 MTUS2 N4BP2L2 NCAPH2 NHLH1 NIF3L1 NOTCH2NLA NUP62 NUTM1 PDE9A PHC2 PRKG1 RBBP8 REL RELA RINT1 RLIM ROCK1 SAXO1 SKP1 SMAD2 SOX5 SP1 SSX2IP STAT1 STAT3 STIP1 TAL1 TAL2 TFPT TLE5 TLX3 TRIM23 TRIM54 TRIP6 TSC22D4 TUFT1 UBA6 UBE2I ZFP64 ZNF24
Entrez ID		22924	4005
HPRD ID		16156	01586
Ensembl ID		ENSG00000084764	ENSG00000135363
Uniprot IDs		Q9UPY8	P25791
PDB IDs		1WYO 3CO1 3JAK 3JAL 3JAR 3TQ7	2XJY 2XJZ 2YPA 4KFZ
Enriched GO Terms of Interacting Partners?
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