MAPRE3 and CLASP1

Number of citations of the paper that reports this interaction (PubMedID 15631994)
177

Data Source:
HPRD (in vivo, in vitro)

		MAPRE3	CLASP1
Description		microtubule associated protein RP/EB family member 3	cytoplasmic linker associated protein 1
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GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Microtubule Midbody Microtubule Plus-end Spindle Midzone Mitotic Spindle Astral Microtubule End	Kinetochore Condensed Chromosome Kinetochore Cell Golgi Apparatus Centrosome Kinetochore Microtubule Cytosol Spindle Microtubule Cytoplasmic Microtubule Focal Adhesion Cell Cortex Membrane Cortical Microtubule Cytoskeleton Centrosomal Corona Microtubule Plus-end Basal Cortex
	Molecular Function	Protein Binding Microtubule Binding Protein C-terminus Binding Protein Kinase Binding Identical Protein Binding Microtubule Plus-end Binding	Dystroglycan Binding Protein Binding Microtubule Binding Kinetochore Binding Microtubule Plus-end Binding
	Biological Process	Protein Localization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule Polymerization Protein Localization To Microtubule Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Transcription, DNA-templated Spindle Assembly Cell Division Positive Regulation Of Microtubule Plus-end Binding Protein Localization To Microtubule Plus-end	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Microtubule Bundle Formation Vesicle Targeting Microtubule Nucleation Negative Regulation Of Microtubule Depolymerization Golgi Organization Mitotic Spindle Organization Establishment Or Maintenance Of Cell Polarity Regulation Of G2/M Transition Of Mitotic Cell Cycle Exit From Mitosis Regulation Of Gastrulation Positive Regulation Of Epithelial Cell Migration Regulation Of Epithelial To Mesenchymal Transition Astral Microtubule Organization Microtubule Organizing Center Organization Negative Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of Microtubule Polymerization Microtubule Anchoring Establishment Of Mitotic Spindle Localization Positive Regulation Of Exocytosis Establishment Of Spindle Orientation Cell Division Negative Regulation Of Stress Fiber Assembly Regulation Of Focal Adhesion Assembly Regulation Of Microtubule Cytoskeleton Organization Positive Regulation Of Extracellular Matrix Disassembly Establishment Of Epithelial Cell Polarity Mitotic Spindle Assembly Ciliary Basal Body-plasma Membrane Docking Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Positive Regulation Of Basement Membrane Assembly Involved In Embryonic Body Morphogenesis
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Role of ABL in ROBO-SLIT signaling Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins Mitotic Prometaphase AURKA Activation by TPX2 EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708) Post bronchodilator FEV1/FVC ratio ( 26634245)	Chloride levels ( 29403010) Cough in response to angiotensin-converting enzyme inhibitor drugs ( 28084903) HDL cholesterol x physical activity interaction (1df test) ( 30670697) HDL cholesterol x physical activity interaction (2df test) ( 30670697) Metabolite levels ( 23823483) Potassium levels ( 29403010)
Interacting Genes		22 interacting genes: APC2 AURKA AURKB CLASP1 DCTN2 DOK4 EIF4E2 FXR2 GTSE1 JUN KIF19 LMO2 MAPRE1 MAPRE2 PSMA1 PSMB1 RAB1A SDCBP SIAH1 SLAIN1 TROAP TXN2	10 interacting genes: CKAP5 JAKMIP2 MAP4 MAPRE1 MAPRE3 MARK3 MTNR1A MTNR1B SRPK2 YWHAG
Entrez ID		22924	23332
HPRD ID		16156	09322
Ensembl ID		ENSG00000084764	ENSG00000074054
Uniprot IDs		Q9UPY8	Q7Z460
PDB IDs		1WYO 3CO1 3JAK 3JAL 3JAR 3TQ7	4K92 6MQ5 6MQ7
Enriched GO Terms of Interacting Partners?
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