FBL and KLF6

Number of citations of the paper that reports this interaction (PubMedID 17636026)
44

Data Source:
BioGRID (pull down)

		FBL	KLF6
Description		fibrillarin	Kruppel like factor 6
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Dense Fibrillar Component Granular Component Nucleus Nucleoplasm Chromosome Nucleolus Cajal Body Membrane Box C/D SnoRNP Complex Small-subunit Processome Extracellular Exosome	Nuclear Chromatin Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	TFIID-class Transcription Factor Complex Binding RNA Binding Protein Binding RRNA Methyltransferase Activity ATPase Binding Histone-glutamine Methyltransferase Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Box C/D SnoRNA 3'-end Processing Osteoblast Differentiation RRNA Processing RRNA Methylation SnoRNA Localization Histone Glutamine Methylation	Regulation Of Transcription By RNA Polymerase II B Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Asthma (bronchodilator response) ( 23508266) Coronary artery calcification ( 23870195) Diastolic blood pressure ( 27841878) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Heel bone mineral density ( 30598549 28869591) Multiple sclerosis ( 31604244) Plasma anti-thyroglobulin levels ( 29678681)
Interacting Genes		17 interacting genes: DDX17 DDX5 ERG KLF6 MAP3K14 PIN4 PRMT1 PRMT3 PRMT6 PSMB6 RUVBL1 RUVBL2 SMN1 SMN2 SNRPN TAF9 TBC1D17	16 interacting genes: APOM APP CELSR2 EHMT2 FBL GTF3C1 HDAC3 KLF4 LCOR NOP56 NUFIP1 PNO1 POLA2 SP1 TAF9 TP53
Entrez ID		2091	1316
HPRD ID		00617	03632
Ensembl ID		ENSG00000105202	ENSG00000067082
Uniprot IDs		P22087	D3GC14 Q99612
PDB IDs		2IPX
Enriched GO Terms of Interacting Partners?
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