FBL and PRMT3

Number of citations of the paper that reports this interaction (PubMedID 16157300)
19

Data Source:
BioGRID (enzymatic study)

		FBL	PRMT3
Description		fibrillarin	protein arginine methyltransferase 3
Image
GO Annotations	Cellular Component	Fibrillar Center Dense Fibrillar Component Granular Component Nucleus Nucleoplasm Chromosome Nucleolus Cajal Body Membrane Box C/D SnoRNP Complex Small-subunit Processome Extracellular Exosome	Nucleus Cytoplasm Cytosol
	Molecular Function	TFIID-class Transcription Factor Complex Binding RNA Binding Protein Binding RRNA Methyltransferase Activity ATPase Binding Histone-glutamine Methyltransferase Activity	Nucleic Acid Binding Protein Binding Methyltransferase Activity Protein-arginine N-methyltransferase Activity Ribosome Binding Metal Ion Binding
	Biological Process	Box C/D SnoRNA 3'-end Processing Osteoblast Differentiation RRNA Processing RRNA Methylation SnoRNA Localization Histone Glutamine Methylation	Protein Methylation Negative Regulation Of Protein Ubiquitination Peptidyl-arginine N-methylation
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	RMTs methylate histone arginines Protein methylation
Drugs			S-adenosyl-L-homocysteine
Diseases
GWAS			Carotid intima media thickness (maximum) ( 31801372) Number of alcoholic drinks required to feel an effect (long-term average) ( 31270906) Pursuit maintenance gain ( 29064472) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)
Interacting Genes		17 interacting genes: DDX17 DDX5 ERG KLF6 MAP3K14 PIN4 PRMT1 PRMT3 PRMT6 PSMB6 RUVBL1 RUVBL2 SMN1 SMN2 SNRPN TAF9 TBC1D17	8 interacting genes: FBL HNRNPA1 PABPN1 PPARD RASSF2 RPS2 STAT1 TSC22D2
Entrez ID		2091	10196
HPRD ID		00617	11934
Ensembl ID		ENSG00000105202	ENSG00000185238
Uniprot IDs		P22087	O60678 Q8WUV3
PDB IDs		2IPX	2FYT 3SMQ 4HSG 4QQN 4RYL
Enriched GO Terms of Interacting Partners?
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