DLST and CCDC86

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DLST	CCDC86
Description		dihydrolipoamide S-succinyltransferase	coiled-coil domain containing 86
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Membrane Oxoglutarate Dehydrogenase Complex	Nucleoplasm Nucleolus
	Molecular Function	Dihydrolipoyllysine-residue Succinyltransferase Activity Protein Binding Transferase Activity, Transferring Acyl Groups	RNA Binding Protein Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Tricarboxylic Acid Cycle 2-oxoglutarate Metabolic Process Succinyl-CoA Metabolic Process Lysine Catabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Histone Succinylation	Viral Process
Pathways		Glyoxylate metabolism and glycine degradation Lysine catabolism Citric acid cycle (TCA cycle)
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Mood instability ( 29187730) Non-small cell lung cancer ( 23144319)	Wegener's granulomatosis ( 23740775)
Interacting Genes		15 interacting genes: ARIH2 CCDC86 DLG5 FLII NAP1L1 NDRG1 OGDH PAK4 PFN2 RUSC2 SCFD1 TUBB4B UMPS ZBTB16 ZHX1	9 interacting genes: AHNAK C9orf153 CPSF7 DLST MS4A14 MS4A15 MS4A8 SRPK2 TUT1
Entrez ID		1743	79080
HPRD ID		00520	08322
Ensembl ID		ENSG00000119689	ENSG00000110104
Uniprot IDs		A0A024R6C9 B7Z6J1 P36957	Q9H6F5
PDB IDs
Enriched GO Terms of Interacting Partners?
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