DLST and SCFD1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DLST	SCFD1
Description		dihydrolipoamide S-succinyltransferase	sec1 family domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Membrane Oxoglutarate Dehydrogenase Complex	Endoplasmic Reticulum Membrane Golgi-associated Vesicle Cis-Golgi Network Cytosol Plasma Membrane Golgi Cisterna Membrane
	Molecular Function	Dihydrolipoyllysine-residue Succinyltransferase Activity Protein Binding Transferase Activity, Transferring Acyl Groups	Protein Binding Syntaxin Binding Protein-containing Complex Binding Protein N-terminus Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Tricarboxylic Acid Cycle 2-oxoglutarate Metabolic Process Succinyl-CoA Metabolic Process Lysine Catabolic Process L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Histone Succinylation	Cell Morphogenesis Response To Hypoxia Retrograde Vesicle-mediated Transport, Golgi To ER Post-Golgi Vesicle-mediated Transport Vesicle Docking Involved In Exocytosis Response To Toxic Substance Protein Transport COPII Vesicle Coating Regulation Of Protein Transport Regulation Of ER To Golgi Vesicle-mediated Transport Toxin Transport Negative Regulation Of Autophagosome Assembly
Pathways		Glyoxylate metabolism and glycine degradation Lysine catabolism Citric acid cycle (TCA cycle)	COPII-mediated vesicle transport
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Mood instability ( 29187730) Non-small cell lung cancer ( 23144319)	Amyotrophic lateral sclerosis ( 29566793 27455348) Cognitive decline (age-related) ( 28078323) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		15 interacting genes: ARIH2 CCDC86 DLG5 FLII NAP1L1 NDRG1 OGDH PAK4 PFN2 RUSC2 SCFD1 TUBB4B UMPS ZBTB16 ZHX1	6 interacting genes: DLST HECTD1 PPBP STX5 USO1 USP22
Entrez ID		1743	23256
HPRD ID		00520	10210
Ensembl ID		ENSG00000119689	ENSG00000092108
Uniprot IDs		A0A024R6C9 B7Z6J1 P36957	B7Z5N7 B7Z738 Q8WVM8
PDB IDs
Enriched GO Terms of Interacting Partners?
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