JMY and CCDC136

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		JMY	CCDC136
Description		junction mediating and regulatory protein, p53 cofactor	coiled-coil domain containing 136
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytoskeleton Cell Leading Edge	Acrosomal Membrane Integral Component Of Membrane
	Molecular Function	Transcription Coactivator Activity Actin Binding Protein Binding Arp2/3 Complex Binding
	Biological Process	DNA Repair Regulation Of Transcription By RNA Polymerase II Cell Cycle Arrest Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Apoptotic Process Positive Regulation Of DNA-binding Transcription Factor Activity 'de Novo' Actin Filament Nucleation Actin Polymerization-dependent Cell Motility Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Nucleic Acid-templated Transcription	Acrosome Assembly Spermatogenesis Single Fertilization
Pathways		Regulation of TP53 Activity through Methylation
Drugs
Diseases
GWAS		Blood and toenail selenium levels ( 25343990) Toenail selenium levels ( 25343990)	Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		5 interacting genes: CCDC136 EP300 F2RL1 MDM2 TTC5	64 interacting genes: ABT1 AQP1 ATP5PO ATXN1 BARD1 BLOC1S6 BYSL C1orf216 CBX8 CCDC146 CCHCR1 CDC5L CDK2AP1 CEP57L1 COIL CWF19L2 DISC1 ENKD1 FAM107A FAM161A GFI1B HAUS1 HDAC4 HGS HMG20A HMG20B JMY KANSL1 KAT5 KIFC3 LENG1 MAGEB4 MOS NDN NEBL PDLIM5 PKN2 PPP1R18 PRPF31 PSMD9 RAB33A SHFL SMARCE1 TBRG1 TCEA2 TNNT1 TXLNA UBQLN4 USP2 WT1 ZBTB38 ZC2HC1C ZNF20 ZNF230 ZNF250 ZNF408 ZNF417 ZNF490 ZNF564 ZNF572 ZNF581 ZNF587 ZNF688 ZSCAN26
Entrez ID		133746	64753
HPRD ID		05045	10887
Ensembl ID		ENSG00000152409	ENSG00000128596
Uniprot IDs		Q8N9B5	A0A024R758 Q96JN2
PDB IDs
Enriched GO Terms of Interacting Partners?
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