CPEB2 and SORBS3

Number of citations of the paper that reports this interaction (PubMedID 22157746)
30

Data Source:
BioGRID (two hybrid)

		CPEB2	SORBS3
Description		cytoplasmic polyadenylation element binding protein 2	sorbin and SH3 domain containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Neuron Projection Synapse Messenger Ribonucleoprotein Complex	Nucleus Cytosol Cytoskeleton Focal Adhesion
	Molecular Function	Translation Repressor Activity, MRNA Regulatory Element Binding RNA Binding MRNA 3'-UTR Binding GTPase Inhibitor Activity Translation Factor Activity, RNA Binding MRNA 3'-UTR AU-rich Region Binding Ribosome Binding Ribosomal Large Subunit Binding Ribosomal Small Subunit Binding	Structural Constituent Of Cytoskeleton Protein Binding Transcription Factor Binding Vinculin Binding
	Biological Process	Translation Cellular Response To Insulin Stimulus Negative Regulation Of GTPase Activity Cellular Response To Oxidative Stress Cellular Response To Arsenic-containing Substance Cellular Response To Hypoxia Negative Regulation Of Cytoplasmic Translational Elongation Negative Regulation Of Cytoplasmic Translation	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Actin Filament Organization Cell Adhesion Cell-substrate Adhesion Positive Regulation Of MAPK Cascade Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Stress Fiber Assembly
Pathways			Smooth Muscle Contraction
Drugs
Diseases
GWAS		Cognitive flexibility ( 30134085)	Diastolic blood pressure ( 30224653) HIV-1 viral setpoint ( 20205591) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Parkinson's disease ( 28892059)
Interacting Genes		21 interacting genes: ATG2A ATP1B2 BSCL2 C2CD2L CAPN15 COPS7A ERI3 GAA GABBR1 GPX7 KEAP1 MT-ATP6 NECAB2 OTUB1 PIGS PSAP PUF60 SEMA4B SORBS3 SPARC TUBA1A	46 interacting genes: ABL1 ADAM15 ADAMTSL4 ARNT2 CBLB CPEB2 CPNE2 CPSF7 DDX17 DIP2A DLG5 DMRTB1 DVL2 EFS EIF3H FASLG FLOT1 HNRNPK HNRNPUL1 INPPL1 KIAA0408 KIAA1217 MAPK1 MAPK3 NCK1 NCKIPSD NOTCH3 PAK2 PAK5 RBMX SAFB2 SAXO1 SH2D4A SOCS7 SRCIN1 TBC1D22B TRIM23 TRIM27 TRIM41 VARS2 VPS37B VPS37C ZBED1 ZBTB25 ZBTB7B ZC4H2
Entrez ID		132864	10174
HPRD ID		16744	11535
Ensembl ID		ENSG00000137449	ENSG00000120896
Uniprot IDs		Q7Z5Q1	O60504
PDB IDs			2CT3 2DLM 2NWM 2YUP
Enriched GO Terms of Interacting Partners?
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