COPA and ARFGAP1

Number of citations of the paper that reports this interaction (PubMedID 12379802)
73

Data Source:
HPRD (in vivo, in vitro)

		COPA	ARFGAP1
Description		COPI coat complex subunit alpha	ADP ribosylation factor GTPase activating protein 1
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GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Cytoplasm Endoplasmic Reticulum Membrane Cytosol Membrane COPI Vesicle Coat Transport Vesicle Growth Cone Extracellular Exosome	Golgi Membrane Cytosol Postsynaptic Density Synapse
	Molecular Function	MRNA Binding Hormone Activity Structural Molecule Activity	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Signal Transduction Pancreatic Juice Secretion Protein Localization To Axon Protein Localization To Cell Leading Edge	ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Protein Transport Regulation Of Endocytosis Regulation Of ARF Protein Signal Transduction IRE1-mediated Unfolded Protein Response Positive Regulation Of GTPase Activity
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	XBP1(S) activates chaperone genes COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Breast size ( 27182965)
Interacting Genes		14 interacting genes: ARCN1 ARFGAP1 COPB2 COPE MTNR1B PDGFRB SACM1L SCYL1 SLC25A11 STX8 TMED10 TMED2 WBP1 WBP2	34 interacting genes: APOB APOC3 APOE APP ARF1 ASB10 COPA COPS5 CSNK1D CYTH2 FOS GABARAPL2 GGCX GRN HRAS KDELR1 KRTAP10-9 KRTAP3-2 KRTAP9-2 LRRK2 MAP1LC3B MED27 PRKACB RAB23 RABGAP1L RASIP1 REEP5 RFC3 RGS2 RPL11 SMN1 TK1 TMED2 TRIM23
Entrez ID		1314	55738
HPRD ID		03564	06443
Ensembl ID		ENSG00000122218	ENSG00000101199
Uniprot IDs		P53621	Q53F62 Q8N6T3
PDB IDs		6PBG 6TZT 6U3V	3DWD 3O47
Enriched GO Terms of Interacting Partners?
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