COPA and STX8

Number of citations of the paper that reports this interaction (PubMedID 12388752)
47

Data Source:
HPRD (in vivo)

		COPA	STX8
Description		COPI coat complex subunit alpha	syntaxin 8
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Cytoplasm Endoplasmic Reticulum Membrane Cytosol Membrane COPI Vesicle Coat Transport Vesicle Growth Cone Extracellular Exosome	Lysosomal Membrane Endosome Early Endosome Late Endosome Endoplasmic Reticulum Trans-Golgi Network Cytosol Integral Component Of Plasma Membrane Endomembrane System Integral Component Of Membrane SNARE Complex Late Endosome Membrane Vesicle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	MRNA Binding Hormone Activity Structural Molecule Activity	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity Syntaxin Binding Ubiquitin Protein Ligase Binding
	Biological Process	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Signal Transduction Pancreatic Juice Secretion Protein Localization To Axon Protein Localization To Cell Leading Edge	Intracellular Protein Transport Vesicle Fusion Endosome To Lysosome Transport Early Endosome To Late Endosome Transport Vesicle Docking Cellular Response To Interferon-gamma Regulation Of Protein Localization To Plasma Membrane
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Breast size ( 27182965)	Blood protein levels ( 30072576) Borderline personality disorder ( 28632202) HDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507)
Interacting Genes		14 interacting genes: ARCN1 ARFGAP1 COPB2 COPE MTNR1B PDGFRB SACM1L SCYL1 SLC25A11 STX8 TMED10 TMED2 WBP1 WBP2	18 interacting genes: ACVR1 AQP2 CALM1 CLN8 COPA CREB3 LMNA NAPA NAPG NSF STX1A STX4 STX7 TGFBR1 VPS11 VPS18 VTI1B WDR91
Entrez ID		1314	9482
HPRD ID		03564	05012
Ensembl ID		ENSG00000122218	ENSG00000170310
Uniprot IDs		P53621	Q9UNK0
PDB IDs		6PBG 6TZT 6U3V
Enriched GO Terms of Interacting Partners?
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