COPA and TMED2

Number of citations of the paper that reports this interaction (PubMedID 8703076)
103

Data Source:
HPRD (in vitro)

		COPA	TMED2
Description		COPI coat complex subunit alpha	transmembrane p24 trafficking protein 2
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GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Cytoplasm Endoplasmic Reticulum Membrane Cytosol Membrane COPI Vesicle Coat Transport Vesicle Growth Cone Extracellular Exosome	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle COPI-coated Vesicle COPI-coated Vesicle Membrane Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Zymogen Granule Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	MRNA Binding Hormone Activity Structural Molecule Activity	Protein Binding
	Biological Process	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Signal Transduction Pancreatic Juice Secretion Protein Localization To Axon Protein Localization To Cell Leading Edge	Neural Tube Closure Maternal Placenta Development Heart Looping Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Golgi Organization Positive Regulation Of Gene Expression Somite Rostral/caudal Axis Specification Negative Regulation Of GTPase Activity Multicellular Organism Growth Cargo Loading Into Vesicle Post-anal Tail Morphogenesis COPI Coating Of Golgi Vesicle COPII Vesicle Coating Labyrinthine Layer Blood Vessel Development Protein Localization To Plasma Membrane
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Pre-NOTCH Processing in Golgi COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Breast size ( 27182965)	Educational attainment ( 25201988) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		14 interacting genes: ARCN1 ARFGAP1 COPB2 COPE MTNR1B PDGFRB SACM1L SCYL1 SLC25A11 STX8 TMED10 TMED2 WBP1 WBP2	9 interacting genes: AKT2 ARF1 ARFGAP1 COPA GOLGA2 GORASP1 GORASP2 SEC23B TMED10
Entrez ID		1314	10959
HPRD ID		03564	17984
Ensembl ID		ENSG00000122218	ENSG00000086598
Uniprot IDs		P53621	Q15363 Q6FHT8
PDB IDs		6PBG 6TZT 6U3V	5AZW
Enriched GO Terms of Interacting Partners?
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