FCHO2 and EPS15L1

Number of citations of the paper that reports this interaction (PubMedID 27237791)
24

Data Source:
BioGRID (pull down)

		FCHO2	EPS15L1
Description		FCH and mu domain containing endocytic adaptor 2	epidermal growth factor receptor pathway substrate 15 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Clathrin-coated Pit Clathrin-coated Vesicle Presynaptic Endocytic Zone Membrane	Nucleus Cytosol Plasma Membrane Membrane Clathrin Coat Of Coated Pit
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Cytoskeletal Protein Binding Phosphatidylinositol Binding Identical Protein Binding	Calcium Ion Binding Protein Binding Cadherin Binding
	Biological Process	Membrane Invagination Clathrin Coat Assembly Synaptic Vesicle Endocytosis Membrane Organization Clathrin-dependent Endocytosis Protein Localization To Plasma Membrane	Endocytosis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Membrane Organization
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	EGFR downregulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Aspartate aminotransferase levels ( 29403010) Discordance in emotional problems in monozygotic twins ( 27043157) Eyebrow thickness ( 26926045) Factor VIII levels ( 30586737) Heel bone mineral density ( 30598549) Immunoglobulin measurement (zinc sulfate turbidity test) ( 29403010) Monobrow thickness ( 26926045) Non-albumin protein levels ( 29403010) Red cell distribution width ( 27863252) Serum albumin level ( 29403010) Small cell lung carcinoma ( 28604730) vWF levels ( 30586737)	Eosinophil percentage of granulocytes ( 27863252) Lymphocyte counts ( 29403010 27863252) Lymphocyte percentage of white cells ( 27863252) Monocyte percentage of white cells ( 27863252) Multiple sclerosis ( 31604244 22190364 24076602) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 27863252) White blood cell count ( 27863252 21738480) White matter integrity ( 23218918)
Interacting Genes		7 interacting genes: DAB2 EPS15 EPS15L1 ITSN1 MRPS27 RHOU UBC	12 interacting genes: AGFG1 AGFG2 EPN1 FCHO1 FCHO2 GNG5 ITSN1 ITSN2 SGIP1 STON2 TRAPPC2B UBC
Entrez ID		115548	58513
HPRD ID		13319	09445
Ensembl ID		ENSG00000157107	ENSG00000127527
Uniprot IDs		Q0JRZ9	A0A024R7G6 Q9UBC2
PDB IDs		2V0O
Enriched GO Terms of Interacting Partners?
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