CHRM2 and GPRASP1

Number of citations of the paper that reports this interaction (PubMedID 15086532)
34

Data Source:
BioGRID (pull down)

		CHRM2	GPRASP1
Description		cholinergic receptor muscarinic 2	G protein-coupled receptor associated sorting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Cell Junction Dendrite Clathrin-coated Vesicle Membrane Asymmetric Synapse Symmetric Synapse Neuronal Cell Body Axon Terminus Synapse Glutamatergic Synapse Cholinergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane	Cytosol
	Molecular Function	G Protein-coupled Receptor Activity G Protein-coupled Serotonin Receptor Activity G Protein-coupled Acetylcholine Receptor Activity Neurotransmitter Receptor Activity Arrestin Family Protein Binding	Protein Binding
	Biological Process	Regulation Of Smooth Muscle Contraction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Chemical Synaptic Transmission Nervous System Development Regulation Of Heart Contraction Response To Virus Membrane Organization G Protein-coupled Serotonin Receptor Signaling Pathway Regulation Of Synaptic Vesicle Exocytosis	Endosome To Lysosome Transport G Protein-coupled Receptor Catabolic Process
Pathways		Muscarinic acetylcholine receptors G alpha (i) signalling events Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs		Succinylcholine Ziprasidone Disopyramide Amitriptyline Ipratropium bromide Olanzapine Metixene Terfenadine Clozapine Trihexyphenidyl Oxyphencyclimine Procyclidine Ethopropazine Loxapine Carbachol Promazine Hyoscyamine Cyproheptadine Pethidine Imipramine Methylscopolamine bromide Gallamine Triethiodide Darifenacin Tridihexethyl Triflupromazine Anisotropine Methylbromide Nortriptyline Amoxapine Cinnarizine Atropine Nicardipine Paroxetine Homatropine Methylbromide Trimipramine Rocuronium Scopolamine Benzquinamide Propiomazine Cryptenamine Dicyclomine Tropicamide Brompheniramine Cocaine Maprotiline Glycopyrronium Bethanechol Tolterodine Oxybutynin Promethazine Diphenhydramine Pilocarpine Doxacurium chloride Doxepin Flavoxate Desipramine Ketamine Quetiapine Mivacurium Diphenidol Aripiprazole Chlorprothixene Metocurine Pancuronium Pipecuronium Methotrimeprazine Tiotropium Solifenacin Acetylcholine ALKS 27 Fesoterodine Hexocyclium Dimetindene Aclidinium Umeclidinium Dosulepin Etoperidone Imidafenacin Butylscopolamine
Diseases
GWAS		Copper levels ( 26025379) General risk tolerance (MTAG) ( 30643258) Heart rate ( 23583979) Heart rate response to recovery post exercise ( 29769521) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Pulse pressure ( 30224653) Resting heart rate ( 29769521 27798624)
Interacting Genes		10 interacting genes: GNA11 GNA14 GNA15 GNG2 GPRASP1 GPRASP2 GRK5 RGS7 SAG SET	47 interacting genes: ADRB1 ADRB2 AGTR1 ATXN7 C8orf33 CALCR CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CRIP1 CXCR2 F2R F2RL1 GLP1R GLYAT GRM1 GRM5 GRM8 HGH1 HMOX2 HTR7 LAMTOR5 LRP2 MAP7D1 MLNR MTF2 OFD1 OPRD1 OPRK1 OPRL1 OPRM1 OXTR PBK PER1 PFDN1 SNAPIN STMN2 TAC3 TACR1 TACR2 TACR3 TBXA2R TFG TRAF4 VIPR1
Entrez ID		1129	9737
HPRD ID		00328	02333
Ensembl ID		ENSG00000181072	ENSG00000198932
Uniprot IDs		A4D1Q0 P08172 Q6SL56 Q6SL59 Q86SJ1	Q5JY77
PDB IDs		1LUB 3UON 4MQS 4MQT 5YC8 5ZK3 5ZK8 5ZKB 5ZKC 6OIK
Enriched GO Terms of Interacting Partners?
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