CHRM2 and GPRASP2

Number of citations of the paper that reports this interaction (PubMedID 15086532)
34

Data Source:
HPRD (in vitro)

		CHRM2	GPRASP2
Description		cholinergic receptor muscarinic 2	G protein-coupled receptor associated sorting protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Cell Junction Dendrite Clathrin-coated Vesicle Membrane Asymmetric Synapse Symmetric Synapse Neuronal Cell Body Axon Terminus Synapse Glutamatergic Synapse Cholinergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane	Nucleus Cytoplasm
	Molecular Function	G Protein-coupled Receptor Activity G Protein-coupled Serotonin Receptor Activity G Protein-coupled Acetylcholine Receptor Activity Neurotransmitter Receptor Activity Arrestin Family Protein Binding	Amyloid-beta Binding G Protein-coupled Receptor Binding Protein Binding
	Biological Process	Regulation Of Smooth Muscle Contraction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Chemical Synaptic Transmission Nervous System Development Regulation Of Heart Contraction Response To Virus Membrane Organization G Protein-coupled Serotonin Receptor Signaling Pathway Regulation Of Synaptic Vesicle Exocytosis
Pathways		Muscarinic acetylcholine receptors G alpha (i) signalling events Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs		Succinylcholine Ziprasidone Disopyramide Amitriptyline Ipratropium bromide Olanzapine Metixene Terfenadine Clozapine Trihexyphenidyl Oxyphencyclimine Procyclidine Ethopropazine Loxapine Carbachol Promazine Hyoscyamine Cyproheptadine Pethidine Imipramine Methylscopolamine bromide Gallamine Triethiodide Darifenacin Tridihexethyl Triflupromazine Anisotropine Methylbromide Nortriptyline Amoxapine Cinnarizine Atropine Nicardipine Paroxetine Homatropine Methylbromide Trimipramine Rocuronium Scopolamine Benzquinamide Propiomazine Cryptenamine Dicyclomine Tropicamide Brompheniramine Cocaine Maprotiline Glycopyrronium Bethanechol Tolterodine Oxybutynin Promethazine Diphenhydramine Pilocarpine Doxacurium chloride Doxepin Flavoxate Desipramine Ketamine Quetiapine Mivacurium Diphenidol Aripiprazole Chlorprothixene Metocurine Pancuronium Pipecuronium Methotrimeprazine Tiotropium Solifenacin Acetylcholine ALKS 27 Fesoterodine Hexocyclium Dimetindene Aclidinium Umeclidinium Dosulepin Etoperidone Imidafenacin Butylscopolamine
Diseases
GWAS		Copper levels ( 26025379) General risk tolerance (MTAG) ( 30643258) Heart rate ( 23583979) Heart rate response to recovery post exercise ( 29769521) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Pulse pressure ( 30224653) Resting heart rate ( 29769521 27798624)
Interacting Genes		10 interacting genes: GNA11 GNA14 GNA15 GNG2 GPRASP1 GPRASP2 GRK5 RGS7 SAG SET	29 interacting genes: ADRB1 ARHGEF6 BARD1 CALCR CBX8 CEP126 CFAP206 CHRM1 CHRM2 DISC1 FRAT1 HAP1 HRH2 HTR7 HTT LRIF1 MICU2 MYOT NOL4L-DT PRPF3 PTN RPS6KA5 RTL10 STMN2 TCF25 TSPOAP1 TXN TXN2 ZNF688
Entrez ID		1129	114928
HPRD ID		00328	06612
Ensembl ID		ENSG00000181072	ENSG00000158301
Uniprot IDs		A4D1Q0 P08172 Q6SL56 Q6SL59 Q86SJ1	B3KW05 Q96D09
PDB IDs		1LUB 3UON 4MQS 4MQT 5YC8 5ZK3 5ZK8 5ZKB 5ZKC 6OIK
Enriched GO Terms of Interacting Partners?
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