RHOQ and GOPC

Number of citations of the paper that reports this interaction (PubMedID 11162552)
24

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		RHOQ	GOPC
Description		ras homolog family member Q	golgi associated PDZ and coiled-coil motif containing
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Actin Filament Plasma Membrane Cell Cortex Golgi-associated Vesicle Membrane Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Exosome	Golgi Membrane Cytoplasm Lysosomal Membrane Golgi Apparatus Plasma Membrane Postsynaptic Density Membrane Cell Junction Trans-Golgi Network Transport Vesicle Dendrite Golgi-associated Vesicle Membrane Protein-containing Complex
	Molecular Function	GTPase Activity Profilin Binding GTP Binding Protein Kinase Binding GBD Domain Binding	Frizzled Binding Protein Binding Protein C-terminus Binding GTPase Regulator Activity Identical Protein Binding Protein Homodimerization Activity Ion Channel Binding
	Biological Process	Endocytosis Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Cell Shape Cell Migration Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Transcription By RNA Polymerase II GTP Metabolic Process Positive Regulation Of Glucose Import Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Filopodium Assembly Negative Regulation Of Protein Localization To Plasma Membrane	ER To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Spermatid Nucleus Differentiation Negative Regulation Of Anion Channel Activity Protein Transport Cytoplasmic Sequestering Of CFTR Protein Apical Protein Localization Regulation Of Catalytic Activity Negative Regulation Of Protein Localization To Cell Surface
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Rho GTPase cycle RHO GTPases regulate CFTR trafficking	RHO GTPases regulate CFTR trafficking
Drugs
Diseases
GWAS			Atrial fibrillation ( 29892015) Colorectal cancer ( 23266556) Facial emotion recognition (fearful faces) ( 28608620) Night sleep phenotypes ( 27126917)
Interacting Genes		18 interacting genes: CDC42BPG CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 COPB1 COPG1 DOCK8 EXOC7 GOPC PARD6A PARD6B PFN1 PRKCI RAPGEF1 TRIP10 TRIP6 WASL	60 interacting genes: ABCA1 ADRB1 AKIRIN1 ASIC3 BATF BECN1 C17orf67 CD300C CDKN2C CERCAM CFTR CLCN3 CRHR1 CSPG5 DLEU1 DPYD FAM90A1 FAM9B FOSL2 FZD5 FZD8 GOLGA3 GRID1 GRID2 HCK HNRNPLL IGHG3 JUN KPNA1 LCLAT1 MORN4 MRPL1 MYLK MYOCD NOTCH1 NUP62 PARK7 PID1 PWWP3A RELA RHOQ RNF183 RNF220 RPL13AP17 RPS6KA1 RTKN SEMA4G SLC25A18 SPATA8 SSTR5 STARD3 STX6 TGFBR2 VIM VTN ZBTB49 ZNF564 ZNF581 ZNF587 ZSCAN1
Entrez ID		23433	57120
HPRD ID		05791	06024
Ensembl ID		ENSG00000119729	ENSG00000047932
Uniprot IDs		D6W5A7 P17081 V9HWD0	Q9HD26
PDB IDs		2ATX	2DC2 2LOB 4E34 4E35 4JOE 4JOF 4JOG 4JOH 4JOJ 4JOK 4JOP 4JOR 4K6Y 4K72 4K75 4K76 4K78 4NMO 4NMP 4NMQ 4NMR 4NMS 4NMT 4NMV 4Q6H 4Q6S 5IC3 5K4F 6OV7
Enriched GO Terms of Interacting Partners?
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