RHOQ and CDC42EP4

Number of citations of the paper that reports this interaction (PubMedID 10490598)
41

Data Source:
HPRD (in vitro, two hybrid)

		RHOQ	CDC42EP4
Description		ras homolog family member Q	CDC42 effector protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Actin Filament Plasma Membrane Cell Cortex Golgi-associated Vesicle Membrane Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Exosome	Cytoplasm Cytoskeleton Plasma Membrane Adherens Junction Endomembrane System Actin Cytoskeleton Microtubule Cytoskeleton Phagocytic Vesicle
	Molecular Function	GTPase Activity Profilin Binding GTP Binding Protein Kinase Binding GBD Domain Binding	RNA Binding Protein Binding GTP-Rho Binding
	Biological Process	Endocytosis Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Cell Shape Cell Migration Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Transcription By RNA Polymerase II GTP Metabolic Process Positive Regulation Of Glucose Import Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Filopodium Assembly Negative Regulation Of Protein Localization To Plasma Membrane	Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Cellular Response To Interferon-gamma
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Rho GTPase cycle RHO GTPases regulate CFTR trafficking
Drugs
Diseases
GWAS
Interacting Genes		18 interacting genes: CDC42BPG CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 COPB1 COPG1 DOCK8 EXOC7 GOPC PARD6A PARD6B PFN1 PRKCI RAPGEF1 TRIP10 TRIP6 WASL	9 interacting genes: APP BRD2 CDC42 FAM9B LNX1 RHOQ SRPK2 TGFBR1 WDR6
Entrez ID		23433	23580
HPRD ID		05791	08383
Ensembl ID		ENSG00000119729	ENSG00000179604
Uniprot IDs		D6W5A7 P17081 V9HWD0	B2R6D8 Q9H3Q1
PDB IDs		2ATX
Enriched GO Terms of Interacting Partners?
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