PRPF8 and GPKOW

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		PRPF8	GPKOW
Description		pre-mRNA processing factor 8	G-patch domain and KOW motifs
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm U5 SnRNP Membrane Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Spliceosomal Complex
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding U1 SnRNA Binding U2 SnRNA Binding U5 SnRNA Binding K63-linked Polyubiquitin Modification-dependent Protein Binding Pre-mRNA Intronic Binding	RNA Binding Protein Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Cellular Response To Lipopolysaccharide Cellular Response To Tumor Necrosis Factor	MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS		Blood protein levels ( 28240269) Calcium levels ( 20705733) Ischemic stroke ( 29531354) Stroke ( 29531354)
Interacting Genes		14 interacting genes: ABCA1 DHX9 ERG GPKOW HNRNPH2 NEDD4 PIN1 PRPF19 SERPINB2 SND1 SNRNP200 UBC UBE2I ZNF830	17 interacting genes: APP BUD13 CCDC57 FBXO7 GOLGA2 NINL PPP1CA PRPF4 PRPF8 ROPN1 SH3GL1 TCEA2 TERF2IP TRAF2 TRIM23 WDR77 WDR83
Entrez ID		10594	27238
HPRD ID		06295	06737
Ensembl ID		ENSG00000174231	ENSG00000068394
Uniprot IDs		Q6P2Q9	Q92917
PDB IDs		3E9L 3ENB 3JCR 3LRU 4JK7 4JK8 4JK9 4JKA 4JKB 4JKC 4JKD 4JKE 4JKF 4JKG 4JKH 4KIT 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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