PRPF8 and SND1

Number of citations of the paper that reports this interaction (PubMedID 17632523)
32

Data Source:
BioGRID (pull down)

		PRPF8	SND1
Description		pre-mRNA processing factor 8	staphylococcal nuclease and tudor domain containing 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U5 SnRNP Membrane Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Nucleus Cytoplasm Cytosol Membrane RISC Complex Melanosome Extracellular Exosome Dense Body
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding U1 SnRNA Binding U2 SnRNA Binding U5 SnRNA Binding K63-linked Polyubiquitin Modification-dependent Protein Binding Pre-mRNA Intronic Binding	Transcription Coregulator Activity RNA Binding Nuclease Activity Endonuclease Activity Endoribonuclease Activity Protein Binding Cadherin Binding RISC Complex Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Cellular Response To Lipopolysaccharide Cellular Response To Tumor Necrosis Factor	Osteoblast Differentiation RNA Catabolic Process Regulation Of Cell Cycle Process MiRNA Catabolic Process Viral Process Gene Silencing By RNA RNA Phosphodiester Bond Hydrolysis, Endonucleolytic Regulation Of Nucleic Acid-templated Transcription
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	Signaling by BRAF and RAF fusions
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS		Blood protein levels ( 28240269) Calcium levels ( 20705733) Ischemic stroke ( 29531354) Stroke ( 29531354)	Birth weight ( 31043758) Cadmium levels ( 26025379) Coffee consumption ( 31046077) Estimated glomerular filtration rate ( 31152163) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Hemoglobin A1c levels ( 29403010) Number of sexual partners ( 30643258) Offspring birth weight ( 31043758) Type 2 diabetes ( 23532257)
Interacting Genes		14 interacting genes: ABCA1 DHX9 ERG GPKOW HNRNPH2 NEDD4 PIN1 PRPF19 SERPINB2 SND1 SNRNP200 UBC UBE2I ZNF830	21 interacting genes: APP CREBBP CSNK2A1 ESR1 GTF2E1 GTF2E2 LZTR1 MAK MYB MYBL2 PIM1 POLR2A PRPF8 RBPJ RNU1-1 RNU2-1 RNU4-1 RNU5A-1 RNU6-1 STAT6 UBE2I
Entrez ID		10594	27044
HPRD ID		06295	03714
Ensembl ID		ENSG00000174231	ENSG00000197157
Uniprot IDs		Q6P2Q9	A0A140VK49 Q7KZF4
PDB IDs		3E9L 3ENB 3JCR 3LRU 4JK7 4JK8 4JK9 4JKA 4JKB 4JKC 4JKD 4JKE 4JKF 4JKG 4JKH 4KIT 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9	2E6N 2HQE 2HQX 2O4X 3BDL 3OMC 3OMG 4QMG 5M9O
Enriched GO Terms of Interacting Partners?
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