TFG and SEC24A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TFG	SEC24A
Description		trafficking from ER to golgi regulator	SEC24 homolog A, COPII coat complex component
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Endoplasmic Reticulum Exit Site	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Zinc Ion Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling COPII Vesicle Coating	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cholesterol Homeostasis Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process COPII Vesicle Coating Positive Regulation Of Protein Secretion Cargo Loading Into COPII-coated Vesicle
Pathways		COPII-mediated vesicle transport	Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases		Non-small cell lung cancer Thyroid cancer
GWAS
Interacting Genes		32 interacting genes: ANXA11 ARHGEF16 ARL15 BOLL CEP126 CEP55 CRMP1 CSTF2 ERG28 EWSR1 GBP2 GPRASP1 GRB2 HGS HNRNPF MAGED1 MAPK1IP1L MED21 MYOT PEF1 PIN1 PLSCR1 PTPN6 RBPMS RIPPLY2 SEC24A SPG21 STAT5B TOMM70 TRIM25 TSSK2 VPS37C	4 interacting genes: CBFA2T3 EWSR1 TFG TRIP13
Entrez ID		10342	10802
HPRD ID		03932	08456
Ensembl ID		ENSG00000114354	ENSG00000113615
Uniprot IDs		Q05BK6 Q92734	B4E205 O95486
PDB IDs			2NUP 2NUT 3EGD 3EGX 5VNE 5VNF 5VNG 5VNH 5VNI 5VNJ 5VNK 5VNL 5VNM 5VNN 5VNO
Enriched GO Terms of Interacting Partners?
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