TFG and MED21

Number of citations of the paper that reports this interaction (PubMedID 11591653)
41

Data Source:
HPRD (in vivo)

		TFG	MED21
Description		trafficking from ER to golgi regulator	mediator complex subunit 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Endoplasmic Reticulum Exit Site	Ubiquitin Ligase Complex Mediator Complex
	Molecular Function	Protein Binding Identical Protein Binding	Transcription Coregulator Activity Transcription Coactivator Activity DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	ER To Golgi Vesicle-mediated Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling COPII Vesicle Coating	Blastocyst Development Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination Stem Cell Population Maintenance RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II
Pathways		COPII-mediated vesicle transport	PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases		Non-small cell lung cancer Thyroid cancer
GWAS			Dimensional psychopathology (Social) ( 29496196)
Interacting Genes		32 interacting genes: ANXA11 ARHGEF16 ARL15 BOLL CEP126 CEP55 CRMP1 CSTF2 ERG28 EWSR1 GBP2 GPRASP1 GRB2 HGS HNRNPF MAGED1 MAPK1IP1L MED21 MYOT PEF1 PIN1 PLSCR1 PTPN6 RBPMS RIPPLY2 SEC24A SPG21 STAT5B TOMM70 TRIM25 TSSK2 VPS37C	26 interacting genes: BLOC1S6 BRCA1 BTF3 CDK8 CDK9 ELOA ESR1 ESR2 HNF4A HTT MAGEA6 MAGEB4 MED29 PCBD2 POLR2A SKP1 SSC5D TARBP2 TFG THRA THRB TP53 TRIM27 VAV2 ZNF655 ZSCAN1
Entrez ID		10342	9412
HPRD ID		03932	09156
Ensembl ID		ENSG00000114354	ENSG00000152944
Uniprot IDs		Q05BK6 Q92734	A0A024RAW0 Q13503
PDB IDs
Enriched GO Terms of Interacting Partners?
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