TFG and PEF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TFG	PEF1
Description		trafficking from ER to golgi regulator	penta-EF-hand domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Endoplasmic Reticulum Exit Site	Golgi Membrane Cytoplasm Endoplasmic Reticulum COPII Vesicle Coat Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	RNA Binding Calcium Ion Binding Protein Binding Protein Heterodimerization Activity Protein Dimerization Activity Calcium-dependent Protein Binding Protein Binding, Bridging Involved In Substrate Recognition For Ubiquitination
	Biological Process	ER To Golgi Vesicle-mediated Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling COPII Vesicle Coating	ER To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Protein Ubiquitination COPII Vesicle Coating Response To Calcium Ion Positive Regulation Of Protein Monoubiquitination
Pathways		COPII-mediated vesicle transport
Drugs			Calcium Citrate Calcium Phosphate
Diseases		Non-small cell lung cancer Thyroid cancer
GWAS			Body mass index ( 26426971) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Severe aortic features in Marfan syndrome ( 30087447)
Interacting Genes		32 interacting genes: ANXA11 ARHGEF16 ARL15 BOLL CEP126 CEP55 CRMP1 CSTF2 ERG28 EWSR1 GBP2 GPRASP1 GRB2 HGS HNRNPF MAGED1 MAPK1IP1L MED21 MYOT PEF1 PIN1 PLSCR1 PTPN6 RBPMS RIPPLY2 SEC24A SPG21 STAT5B TOMM70 TRIM25 TSSK2 VPS37C	14 interacting genes: ALG2 CALCOCO2 CEP55 CUL3 DAZAP2 DMRTB1 EWSR1 FOXR2 HGS KLHL12 NR0B2 PDCD6 SEC31A TFG
Entrez ID		10342	553115
HPRD ID		03932	10143
Ensembl ID		ENSG00000114354	ENSG00000162517
Uniprot IDs		Q05BK6 Q92734	A0A384MQX5 Q9UBV8
PDB IDs
Enriched GO Terms of Interacting Partners?
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