SEC24A and CBFA2T3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		SEC24A	CBFA2T3
Description		SEC24 homolog A, COPII coat complex component	CBFA2/RUNX1 partner transcriptional co-repressor 3
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat	Golgi Membrane Nucleus Nucleoplasm Nucleolus
	Molecular Function	Protein Binding Zinc Ion Binding	DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cholesterol Homeostasis Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process COPII Vesicle Coating Positive Regulation Of Protein Secretion Cargo Loading Into COPII-coated Vesicle	Response To Hypoxia Negative Regulation Of Cell Proliferation Granulocyte Differentiation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Glycolytic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Aerobic Respiration
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
GWAS			Annualised percent change of cerebrospinal fluid AB1-42 levels ( 31370031) Carotid intima media thickness ( 30510157) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Hair color ( 26926045) Mean corpuscular hemoglobin ( 27863252) Mean platelet volume ( 27863252) Multiple sclerosis ( 31604244) Red vs. brown/black hair color ( 30531825) Social autistic-like traits ( 24133439) Vitiligo ( 27723757)
Interacting Genes		4 interacting genes: CBFA2T3 EWSR1 TFG TRIP13	15 interacting genes: CBFA2T2 GMEB2 HDAC1 HDAC3 MATN2 NUP98 PRKAR2A RUNX1 RUNX1T1 SEC24A TCF3 ZBTB33 ZBTB38 ZBTB4 ZNF652
Entrez ID		10802	863
HPRD ID		08456	04847
Ensembl ID		ENSG00000113615	ENSG00000129993
Uniprot IDs		B4E205 O95486	O75081
PDB IDs		2NUP 2NUT 3EGD 3EGX 5VNE 5VNF 5VNG 5VNH 5VNI 5VNJ 5VNK 5VNL 5VNM 5VNN 5VNO
Enriched GO Terms of Interacting Partners?
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