APC2 and MAPRE3

Number of citations of the paper that reports this interaction (PubMedID 10644998)
42

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		APC2	MAPRE3
Description		APC regulator of WNT signaling pathway 2	microtubule associated protein RP/EB family member 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Cytoplasmic Microtubule Actin Filament Microtubule Cytoskeleton Catenin Complex Midbody Beta-catenin Destruction Complex Lamellipodium Membrane Filamentous Actin Intercellular Bridge Perinuclear Region Of Cytoplasm Postsynapse	Cytoplasm Microtubule Organizing Center Microtubule Midbody Microtubule Plus-end Spindle Midzone Mitotic Spindle Astral Microtubule End
	Molecular Function	Protein Binding Beta-catenin Binding Microtubule Binding Gamma-catenin Binding	Protein Binding Microtubule Binding Protein C-terminus Binding Protein Kinase Binding Identical Protein Binding Microtubule Plus-end Binding
	Biological Process	Microtubule Cytoskeleton Organization Cell Fate Specification Negative Regulation Of Microtubule Depolymerization Pattern Specification Process Wnt Signaling Pathway Cell Migration Regulation Of Cell Differentiation Positive Regulation Of Protein Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Activation Of GTPase Activity	Protein Localization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule Polymerization Protein Localization To Microtubule Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Transcription, DNA-templated Spindle Assembly Cell Division Positive Regulation Of Microtubule Plus-end Binding Protein Localization To Microtubule Plus-end
Pathways
Drugs
Diseases		Colorectal cancer
GWAS		Lean body mass ( 28552196)	Estimated glomerular filtration rate in non-diabetics ( 31451708) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		4 interacting genes: AXIN2 CTNNB1 MAPRE1 MAPRE3	22 interacting genes: APC2 AURKA AURKB CLASP1 DCTN2 DOK4 EIF4E2 FXR2 GTSE1 JUN KIF19 LMO2 MAPRE1 MAPRE2 PSMA1 PSMB1 RAB1A SDCBP SIAH1 SLAIN1 TROAP TXN2
Entrez ID		10297	22924
HPRD ID		09802	16156
Ensembl ID		ENSG00000115266	ENSG00000084764
Uniprot IDs		O95996	Q9UPY8
PDB IDs			1WYO 3CO1 3JAK 3JAL 3JAR 3TQ7
Enriched GO Terms of Interacting Partners?
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