Search Results for: RFX3

19 interactions involving RFX3 - regulatory factor X3 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Symbol Description Pathways Hide Drugs Hide Diseases Hide
Novel AK3 adenylate kinase 3
  • Factors involved in megakaryocyte development and platelet production
Novel CDK1 cyclin dependent kinase 1
  • MAPK3 (ERK1) activation
  • E2F-enabled inhibition of pre-replication complex formation
  • Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
  • Golgi Cisternae Pericentriolar Stack Reorganization
  • APC/C:Cdc20 mediated degradation of Cyclin B
  • Cdc20:Phospho-APC/C mediated degradation of Cyclin A
  • Regulation of APC/C activators between G1/S and early anaphase
  • Phosphorylation of the APC/C
  • Phosphorylation of Emi1
  • Condensation of Prophase Chromosomes
  • MASTL Facilitates Mitotic Progression
  • Resolution of Sister Chromatid Cohesion
  • Condensation of Prometaphase Chromosomes
  • Regulation of PLK1 Activity at G2/M Transition
  • Activation of NIMA Kinases NEK9, NEK6, NEK7
  • Initiation of Nuclear Envelope (NE) Reformation
  • Nuclear Pore Complex (NPC) Disassembly
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Depolymerization of the Nuclear Lamina
  • Anchoring of the basal body to the plasma membrane
  • MAPK6/MAPK4 signaling
  • Ovarian tumor domain proteases
  • TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
  • Regulation of TP53 Degradation
  • Mitotic Prophase
  • G1/S-Specific Transcription
  • Cyclin A/B1/B2 associated events during G2/M transition
  • G2/M DNA replication checkpoint
  • Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
  • The role of GTSE1 in G2/M progression after G2 checkpoint
  • AURKA Activation by TPX2
  • Transcriptional regulation by RUNX2
  • PKR-mediated signaling
  • Indirubin-3'-monoxime
  • Olomoucine
  • Hymenialdisine
  • SU9516
  • Alvocidib
  • Alsterpaullone
  • Seliciclib
  • AT-7519
  • Fostamatinib
  • Avotaciclib
Novel NANS N-acetylneuraminate synthase
  • Sialic acid metabolism
Novel PBRM1 polybromo 1
  • RMTs methylate histone arginines
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • Formation of the polybromo-BAF (pBAF) complex
Novel SLC1A3 solute carrier family 1 member 3
  • Astrocytic Glutamate-Glutamine Uptake And Metabolism
  • Glutamate Neurotransmitter Release Cycle
  • Defective SLC1A3 causes episodic ataxia 6 (EA6)
  • SLC-mediated transport of amino acids
  • Glutamic acid
  • Episodic ataxias
Novel TMEM9B TMEM9 domain family member B
BIN1 bridging integrator 1
  • Clathrin-mediated endocytosis
  • Centronuclear myopathy
CREB1 cAMP responsive element binding protein 1
  • Adenosine phosphate
  • Naloxone
EWSR1 EWS RNA binding protein 1
  • Extraskeletal myxoid chondrosarcoma
  • Myxoid liposarcoma
  • Ewing's sarcoma
  • Clear cell sarcoma of soft tissue
FHL2 four and a half LIM domains 2
  • PPARA activates gene expression
FHL3 four and a half LIM domains 3
IRF6 interferon regulatory factor 6
  • Interferon gamma signaling
  • Interferon alpha/beta signaling
  • IRF6-related disorders, including: Popliteal pterygium syndrome (PPS); Van der Woude syndrome (VWS)
  • Isolated orofacial clefts, including: Cleft lip with or without cleft palate; Cleft palate
MEOX2 mesenchyme homeobox 2
PKNOX1 PBX/knotted 1 homeobox 1
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
RFX1 regulatory factor X1
RFX4 regulatory factor X4
RFX6 regulatory factor X6
  • Regulation of gene expression in beta cells
TRAF2 TNF receptor associated factor 2
  • Caspase activation via Death Receptors in the presence of ligand
  • Regulation by c-FLIP
  • RIPK1-mediated regulated necrosis
  • CASP8 activity is inhibited
  • TNFR1-induced proapoptotic signaling
  • Regulation of TNFR1 signaling
  • TNFR1-induced NF-kappa-B signaling pathway
  • TNFR2 non-canonical NF-kB pathway
  • Regulation of necroptotic cell death
  • TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
  • Ub-specific processing proteases
  • Dimerization of procaspase-8
  • TNF signaling
  • TRAF6 mediated IRF7 activation
  • TRAF6 mediated NF-kB activation
  • TRAF6 mediated NF-kB activation
  • Defective RIPK1-mediated regulated necrosis
  • Regulation of NF-kappa B signaling
TRIP6 thyroid hormone receptor interactor 6

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