NEK9 - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	GZMB	granzyme B	NOTCH2 intracellular domain regulates transcription Pyroptosis Activation, myristolyation of BID and translocation to mitochondria Nuclear events stimulated by ALK signaling in cancer
Novel	IFT43	intraflagellar transport 43	Intraflagellar transport
Novel	JDP2	Jun dimerization protein 2		Pseudoephedrine
Novel	LIN52	lin-52 DREAM MuvB core complex component	Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 Polo-like kinase mediated events Cyclin E associated events during G1/S transition G1/S-Specific Transcription Cyclin A:Cdk2-associated events at S phase entry
Novel	MALL	mal, T cell differentiation protein like
Novel	PALS1	protein associated with LIN7 1, MAGUK p55 family member	Tight junction interactions SARS-CoV-1 targets PDZ proteins in cell-cell junction SARS-CoV-2 targets PDZ proteins in cell-cell junction SARS-CoV-2 targets PDZ proteins in cell-cell junction
Novel	RARG	retinoic acid receptor gamma	Nuclear Receptor transcription pathway Signaling by Retinoic Acid Activation of anterior HOX genes in hindbrain development during early embryogenesis	Adapalene Acitretin Alitretinoin Tretinoin Tazarotene Etretinate Isotretinoin SR11254 BMS-181156 CD564 Dodecyl-Alpha-D-Maltoside BMS184394 Palovarotene LGD-1550 3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acid 3-fluoro-4-[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8,-tetrahydro-naphtalen-2-yl)-acetylamino]-benzoic acid Trifarotene
Novel	RPS6KL1	ribosomal protein S6 kinase like 1
Novel	WDR33	WD repeat domain 33	Transport of Mature mRNA Derived from an Intronless Transcript mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
	BICD2	BICD cargo adaptor 2	COPI-independent Golgi-to-ER retrograde traffic
	CSN2	casein beta	Nuclear signaling by ERBB4 Developmental Lineage of Mammary Gland Alveolar Cells
	GABARAP	GABA type A receptor-associated protein	Macroautophagy TBC/RABGAPs
	MAP1LC3A	microtubule associated protein 1 light chain 3 alpha	Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy
	MAP1LC3B	microtubule associated protein 1 light chain 3 beta	Macroautophagy PINK1-PRKN Mediated Mitophagy TBC/RABGAPs Receptor Mediated Mitophagy Pexophagy Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex SARS-CoV-2 modulates autophagy KEAP1-NFE2L2 pathway
	MBP	myelin basic protein	EGR2 and SOX10-mediated initiation of Schwann cell myelination
	NEK6	NIMA related kinase 6	Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation
	NEK7	NIMA related kinase 7	Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation
	NEK8	NIMA related kinase 8			Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
	PELI2	pellino E3 ubiquitin protein ligase family member 2	Interleukin-1 signaling IRAK1 recruits IKK complex IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
	RAN	RAN, member RAS oncogene family	Rev-mediated nuclear export of HIV RNA Regulation of cholesterol biosynthesis by SREBP (SREBF) NEP/NS2 Interacts with the Cellular Export Machinery Nuclear import of Rev protein MicroRNA (miRNA) biogenesis Transcriptional regulation by small RNAs tRNA processing in the nucleus Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation	Guanosine-5'-Diphosphate

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