| Novel |
MAP3K5
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mitogen-activated protein kinase kinase kinase 5 |
- Oxidative Stress Induced Senescence
- Oxidative Stress Induced Senescence
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ABI1
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abl interactor 1 |
- Regulation of actin dynamics for phagocytic cup formation
- Regulation of actin dynamics for phagocytic cup formation
- VEGFA-VEGFR2 Pathway
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate WASPs and WAVEs
- RAC1 GTPase cycle
- RAC2 GTPase cycle
- RAC3 GTPase cycle
- FCGR3A-mediated phagocytosis
- FCGR3A-mediated phagocytosis
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ABI3
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ABI family member 3 |
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AP2B1
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adaptor related protein complex 2 subunit beta 1 |
- Nef Mediated CD4 Down-regulation
- Retrograde neurotrophin signalling
- Retrograde neurotrophin signalling
- Nef Mediated CD8 Down-regulation
- MHC class II antigen presentation
- EPH-ephrin mediated repulsion of cells
- Recycling pathway of L1
- Recycling pathway of L1
- WNT5A-dependent internalization of FZD4
- WNT5A-dependent internalization of FZD2, FZD5 and ROR2
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
- VLDLR internalisation and degradation
- LDL clearance
- Potential therapeutics for SARS
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BEGAIN
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brain enriched guanylate kinase associated |
- Neurexins and neuroligins
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CARD9
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caspase recruitment domain family member 9 |
- NOD1/2 Signaling Pathway
- CLEC7A (Dectin-1) signaling
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- Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
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CBY2
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chibby family member 2 |
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CCDC57
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coiled-coil domain containing 57 |
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CCDC85B
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coiled-coil domain containing 85B |
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CEP72
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centrosomal protein 72 |
- Regulation of PLK1 Activity at G2/M Transition
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Anchoring of the basal body to the plasma membrane
- AURKA Activation by TPX2
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DCTN1
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dynactin subunit 1 |
- MHC class II antigen presentation
- HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
- XBP1(S) activates chaperone genes
- COPI-mediated anterograde transport
- COPI-independent Golgi-to-ER retrograde traffic
- Signaling by ALK fusions and activated point mutants
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- Perry syndrome
- Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
- Distal hereditary motor neuropathies (dHMN)
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DTNBP1
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dystrobrevin binding protein 1 |
- Golgi Associated Vesicle Biogenesis
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- Hermansky-Pudlak syndrome (HPS)
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FRS3
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fibroblast growth factor receptor substrate 3 |
- FRS-mediated FGFR1 signaling
- FRS-mediated FGFR2 signaling
- FRS-mediated FGFR3 signaling
- FRS-mediated FGFR4 signaling
- RAF/MAP kinase cascade
- Activated NTRK2 signals through FRS2 and FRS3
- RND2 GTPase cycle
- RND1 GTPase cycle
- Signaling by ALK fusions and activated point mutants
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GFAP
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glial fibrillary acidic protein |
- Nuclear signaling by ERBB4
- Chaperone Mediated Autophagy
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GRB2
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growth factor receptor bound protein 2 |
- Interleukin-15 signaling
- Interleukin-15 signaling
- Signaling by CSF3 (G-CSF)
- Signaling by CSF3 (G-CSF)
- STAT5 activation downstream of FLT3 ITD mutants
- Signaling by FLT3 ITD and TKD mutants
- Signaling by FLT3 ITD and TKD mutants
- Signaling by ALK fusions and activated point mutants
- Signaling by LTK
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- Pegademase
- 4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid
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HOOK2
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hook microtubule tethering protein 2 |
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HSF2BP
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heat shock transcription factor 2 binding protein |
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KDM1A
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lysine demethylase 1A |
- HDACs deacetylate histones
- HDMs demethylate histones
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- Regulation of PTEN gene transcription
- Estrogen-dependent gene expression
- NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
- Potential therapeutics for SARS
- Negative Regulation of CDH1 Gene Transcription
- Factors involved in megakaryocyte development and platelet production
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KRT15
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keratin 15 |
- Keratinization
- Formation of the cornified envelope
- Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
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MAGEA11
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MAGE family member A11 |
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